MRI Assessment of Bone Marrow Composition in Osteoporosis.
MRI Assessment of Bone Marrow Composition in Osteoporosis.
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DOI：
10.1007/s11914-020-00562-x
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发表时间：
2020-02
影响因子：
4.3
通讯作者：
中科院分区：
文献类型：
--
作者：
概述使用磁共振成像(MRI)和波谱(MRS)技术量化骨髓成分的最新技术进展，以及在骨质疏松症背景下骨髓脂肪组织(MAT)和骨骼健康之间相互关系的最新发现的摘要。在使用磁共振技术可靠地量化骨髓成分方面，已经有了重大的技术进步。横断面研究表明MAT与骨之间呈负相关，小梁骨与MAT的相关性比皮质骨更强。然而，对垫子和骨骼的纵向研究有限。MAT的含量和成分与常见的脊椎骨折有关。MAT和临床骨折之间的证据更加有限，到目前为止，还没有关于MAT和偶发骨折之间关系的研究报道。越来越多的证据表明，骨髓脂肪在骨骼健康中发挥着积极的作用。可靠的非侵入性量化骨髓成分将有助于开发新的骨质疏松症治疗策略。
To provide an overview on recent technical development for quantifying marrow composition using magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques, as well as a summary on recent findings of interrelationship between marrow adipose tissue (MAT) and skeletal health in the context of osteoporosis. There have been significant technical advances in reliable quantification of marrow composition using MR techniques. Cross-sectional studies have demonstrated a negative correlation between MAT and bone, with trabecular bone associating more strongly with MAT than cortical bone. However, longitudinal studies of MAT and bone are limited. MAT contents and composition have been associated with prevalent vertebral fracture. The evidence between MAT and clinical fracture is more limited, and, to date, no studies have reported on the relationship between MAT and incident fracture. Increasing evidence suggests a dynamic role of marrow fat in skeletal health. Reliable non-invasive quantification of marrow composition will facilitate developing novel treatment strategies for osteoporosis.
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影响因子：
3.3
作者：
Hernando, Diego;Liang, Zhi-Pei;Kellman, Peter
通讯作者：
Kellman, Peter
影响因子：
3.7
作者：
Ferrau, Francesco;Giovinazzo, Salvatore;Cannavo, Salvatore
通讯作者：
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影响因子：
4.8
作者：
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通讯作者：
Tarantino, Umberto
影响因子：
3.3
作者：
Herrmann, Jochen;Krstin, Nina;Habermann, Christian R.
通讯作者：
Habermann, Christian R.
影响因子：
4.1
作者：
Arentsen, Luke;Yagi, Masashi;Hui, Susanta
通讯作者：
Hui, Susanta