The immune landscape of human tumors: Implications for cancer immunotherapy.

The immune landscape of human tumors: Implications for cancer immunotherapy.
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DOI:
10.4161/onci.27456
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发表时间:
2014-01-01
期刊:
影响因子:
7.2
通讯作者:
Galon J
Galon J
中科院分区:
医学2区
文献类型:
--
作者:
Bindea G;Mlecnik B;Angell HK;Galon J

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Understanding the spontaneous immune response of cancer patients is critical for the design of efficient anticancer immunotherapies. The power of integrative tumor immunology approaches allowed for a comprehensive view of the immune system evolution in the course of tumor progression and recurrence. We have demonstrated that tumor-infiltrating immune cells are spatiotemporally regulated, a finding that has profound implications for the development of efficient anticancer immunotherapies.
在合成生物学时代,用于癌症免疫疗法的过继T细胞转移。
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