Neural pathways of embarrassment and their modulation by social anxiety.
Neural pathways of embarrassment and their modulation by social anxiety.
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DOI：
10.1016/j.neuroimage.2015.06.036
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发表时间：
2015-10-01
期刊：
影响因子：
5.7
通讯作者：
Krach S
中科院分区：
文献类型：
--
作者：
Müller-Pinzler L;Gazzola V;Keysers C;Sommer J;Jansen A;Frässle S;Einhäuser W;Paulus FM;Krach S
当人们处于关注的中心，并受到他人的评价时，人类很容易经历尴尬。为了描述这种厌恶时刻的神经基础，我们在一项功能神经成像研究中诱导了人与群体互动过程中真实的尴尬经历。使用一个有三个同盟者的模拟场景，我们研究了观众的存在如何影响生理和神经反应，以及报告的失败和成就的情感体验。结果表明，注意诱导的脑化区域的激活和失败导致唤醒处理系统的激活。在社交焦虑的参与者中，心智活动以及对观众的关注都有所增加。来自前脑岛腹侧和杏仁核的心智区域和觉醒处理系统的信息的汇聚整合形成了尴尬的神经通路。针对(旁)边缘系统中这些尴尬的神经标记物，为开发社交焦虑症的治疗策略提供了新的视角。
While being in the center of attention and exposed to other’s evaluations humans are prone to experience embarrassment. To characterize the neural underpinnings of such aversive moments, we induced genuine experiences of embarrassment during person-group interactions in a functional neuroimaging study. Using a mock-up scenario with three confederates, we examined how the presence of an audience affected physiological and neural responses and the reported emotional experiences of failures and achievements. The results indicated that publicity induced activations in mentalizing areas and failures led to activations in arousal processing systems. Mentalizing activity as well as attention towards the audience were increased in socially anxious participants. The converging integration of information from mentalizing areas and arousal processing systems within the ventral anterior insula and amygdala form the neural pathways of embarrassment. Targeting these neural markers of embarrassment in the (para-)limbic system provides new perspectives for developing treatment strategies for social anxiety disorders.
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DOI：
10.1093/cercor/bhq186
发表时间：
2011-07
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Deen B;Pitskel NB;Pelphrey KA
通讯作者：
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通讯作者：
Nelson, Eric E.
影响因子：
4.8
作者：
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通讯作者：
Keysers, Christian
DOI：
10.1176/appi.ajp.2011.10121740
发表时间：
2011-11
期刊：
The American journal of psychiatry
影响因子：
--
作者：
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通讯作者：
Pine DS
影响因子：
5.7
作者：
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通讯作者：
Milham, Michael P.