Recent Advances in Electrical Neural Interface Engineering: Minimal Invasiveness, Longevity, and Scalability.

Recent Advances in Electrical Neural Interface Engineering: Minimal Invasiveness, Longevity, and Scalability.
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DOI:
10.1016/j.neuron.2020.10.011
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发表时间:
2020-10-28
期刊:
影响因子:
16.2
通讯作者:
Xie C
Xie C
中科院分区:
医学1区
文献类型:
--
作者:
Luan L;Robinson JT;Aazhang B;Chi T;Yang K;Li X;Rathore H;Singer A;Yellapantula S;Fan Y;Yu Z;Xie C

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Electrical neural interfaces serve as direct communication pathways that connect the nervous system with the external world. Technological advances in this domain are providing increasingly more powerful tools to study, restore, and augment neural functions. Yet, the complexities of the nervous system give rise to substantial challenges in the design, fabrication and system-level integration of these functional devices. In this review, we present snapshots of the latest progresses in electrical neural interfaces, with an emphasis on advances that expand the spatiotemporal resolution and extent of mapping and manipulating brain circuits. We include discussions of large-scale, long-lasting neural recording, wireless, miniaturized implants, signal transmission, amplification and processing, as well as the integration of interfaces with optical modalities. We outline the background and rationale of these developments and share insights into the future directions and new opportunities they enable. In this review, Luan, et al, discuss the latest advances in engineering electrical neural interfaces that expand the spatiotemporal resolution and extent of mapping and manipulating brain circuits, covering implanted devices, integrated circuits, signal transmission and processing.
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