OGEE: an online gene essentiality database.
OGEE: an online gene essentiality database.
复制标题
DOI：
10.1093/nar/gkr986
复制
发表时间：
2012-01
影响因子：
14.9
通讯作者：
Bork P
中科院分区：
文献类型：
--
作者：
Chen WH;Minguez P;Lercher MJ;Bork P
OGEE是一个在线性别数据库。它的主要目的是提高我们对基因本质的理解。这是通过收集不仅实验测试的必需和非必需基因，而且相关的基因特征，如表达谱，复制状态，跨物种的保护，进化起源和参与胚胎发育。我们专注于大规模的实验，并用文本挖掘结果补充我们的数据。基因根据其来源被组织成数据集。在数据集上具有可变必要性状态的基因被标记为条件必要的，突出了基因功能和环境之间复杂的相互作用。链接工具允许用户比较不同基因组之间的基因必要性，或比较必需基因与非必需基因的特征，并可视化结果。OGEE可在http://ogeedb.embl.de上免费获得。
OGEE is an Online GEne Essentiality database. Its main purpose is to enhance our understanding of the essentiality of genes. This is achieved by collecting not only experimentally tested essential and non-essential genes, but also associated gene features such as expression profiles, duplication status, conservation across species, evolutionary origins and involvement in embryonic development. We focus on large-scale experiments and complement our data with text-mining results. Genes are organized into data sets according to their sources. Genes with variable essentiality status across data sets are tagged as conditionally essential, highlighting the complex interplay between gene functions and environments. Linked tools allow the user to compare gene essentiality among different gene groups, or compare features of essential genes to non-essential genes, and visualize the results. OGEE is freely available at http://ogeedb.embl.de.
登录
查看更多内容
影响因子：
14.9
作者：
Blake JA;Bult CJ;Kadin JA;Richardson JE;Eppig JT;Mouse Genome Database Group
通讯作者：
Mouse Genome Database Group
影响因子：
9.9
作者：
de Berardinis, Veronique;Vallenet, David;Castelli, Vanina;Besnard, Marielle;Pinet, Agnes;Cruaud, Corinne;Samair, Sumitta;Lechaplais, Christophe;Gyapay, Gabor;Richez, Celine;Durot, Maxime;Kreimeyer, Annett;Le Fevre, Francois;Schaechter, Vincent;Pezo, Valerie;Doering, Volker;Scarpelli, Claude;Medigue, Claudine;Cohen, Georges N.;Marliere, Philippe;Salanoubat, Marcel;Weissenbach, Jean
通讯作者：
Weissenbach, Jean
影响因子：
4.4
作者：
Chaudhuri RR;Allen AG;Owen PJ;Shalom G;Stone K;Harrison M;Burgis TA;Lockyer M;Garcia-Lara J;Foster SJ;Pleasance SJ;Peters SE;Maskell DJ;Charles IG
通讯作者：
Charles IG
影响因子：
7
作者：
Langridge, Gemma C.;Phan, Minh-Duy;Turner, A. Keith
通讯作者：
Turner, A. Keith
影响因子：
64.8
作者：
Jeong, H;Mason, SP;Oltvai, ZN
通讯作者：
Oltvai, ZN