The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics.
The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics.
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DOI：
10.1093/nar/gkq1008
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发表时间：
2011-01
影响因子：
14.9
通讯作者：
Mouse Genome Database Group
中科院分区：
文献类型：
--
作者：
Blake JA;Bult CJ;Kadin JA;Richardson JE;Eppig JT;Mouse Genome Database Group
小鼠基因组数据库（MGD）是实验室小鼠的社区模式生物数据库，也是小鼠基因表型和功能注释的权威来源。MGD包括一个完整的小鼠基因和基因组特征目录，可集成访问遗传，基因组和表型信息，所有这些都有助于进一步使用小鼠作为研究人类生物学和疾病的模型系统。MGD是小鼠基因组信息学（MGI，http：//www.informatics.jax.org/）资源的主要组成部分。MGD包含小鼠表型的标准化描述，小鼠模型与人类遗传疾病之间的关联，DNA和蛋白质序列数据的广泛整合，基因组和基因组变异信息的标准化表示。通过人工管理生物医学文献、个体研究者的直接贡献和从主要信息资源中心下载来获得数据并进行整合。MGD与生物信息学社区合作开发和使用生物医学本体，如基因本体（GO）和哺乳动物表型（MP）本体。对小鼠基因组数据库的主要改进包括全面更新遗传图谱，实施新的基因组特征分类术语，开发重组酶（cre）门户网站，并纳入国际敲除小鼠联盟（IKMC）产生的所有等位基因。
The Mouse Genome Database (MGD) is the community model organism database for the laboratory mouse and the authoritative source for phenotype and functional annotations of mouse genes. MGD includes a complete catalog of mouse genes and genome features with integrated access to genetic, genomic and phenotypic information, all serving to further the use of the mouse as a model system for studying human biology and disease. MGD is a major component of the Mouse Genome Informatics (MGI, http://www.informatics.jax.org/) resource. MGD contains standardized descriptions of mouse phenotypes, associations between mouse models and human genetic diseases, extensive integration of DNA and protein sequence data, normalized representation of genome and genome variant information. Data are obtained and integrated via manual curation of the biomedical literature, direct contributions from individual investigators and downloads from major informatics resource centers. MGD collaborates with the bioinformatics community on the development and use of biomedical ontologies such as the Gene Ontology (GO) and the Mammalian Phenotype (MP) Ontology. Major improvements to the Mouse Genome Database include comprehensive update of genetic maps, implementation of new classification terms for genome features, development of a recombinase (cre) portal and inclusion of all alleles generated by the International Knockout Mouse Consortium (IKMC).
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影响因子：
14.9
作者：
Blake JA;Bult CJ;Eppig JT;Kadin JA;Richardson JE;Mouse Genome Database Group
通讯作者：
Mouse Genome Database Group
影响因子：
14.9
作者：
Wilming, L. G.;Gilbert, J. G. R.;Harrow, J. L.
通讯作者：
Harrow, J. L.
鼠标基因表达数据库（GXD）：2007更新。
影响因子：
14.9
作者：
Smith, Constance M.;Finger, Jacqueline H.;Hayamizu, Terry F.;McCright, Ingeborg J.;Eppig, Janan T.;Kadin, James A.;Richardson, Joel E.;Ringwald, Martin
通讯作者：
Ringwald, Martin
影响因子：
14.9
作者：
Pruitt KD;Tatusova T;Klimke W;Maglott DR
通讯作者：
Maglott DR
影响因子：
14.9
作者：
Ringwald M;Iyer V;Mason JC;Stone KR;Tadepally HD;Kadin JA;Bult CJ;Eppig JT;Oakley DJ;Briois S;Stupka E;Maselli V;Smedley D;Liu S;Hansen J;Baldock R;Hicks GG;Skarnes WC
通讯作者：
Skarnes WC