The neural basis of value accumulation in intertemporal choice.

The neural basis of value accumulation in intertemporal choice.
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在跨颞选择中价值积累的神经基础。

DOI:
10.1111/ejn.12997
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发表时间:
2015-09
期刊:
The European journal of neuroscience
影响因子:
--
通讯作者:
McClure SM
McClure SM
中科院分区:
其他
文献类型:
--
作者:
Rodriguez CA;Turner BM;Van Zandt T;McClure SM

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做出跨期选择(在不同时间点可获得的奖励之间做出选择)需要确定和比较可获得奖励的主观价值。几项研究发现了识别在跨期选择中编码主观价值的神经系统的趋同证据。然而,在主观价值的基础上产生跨期决策的神经机制还没有被研究。通过对功能性磁共振成像数据的基于模型和连通性的分析,我们研究了价值积累过程背后的神经机制,主观价值通过这一过程指导跨期决策。我们的结果表明,背内侧额叶皮质、双侧顶后皮质和双侧外侧前额叶皮质都参与了动作选择主观价值的积累。我们的发现建立了一个机制框架来理解额顶叶对跨期选择的贡献,并暗示额顶叶皮质的价值积累过程可能是基于价值的选择的一般机制。
Making intertemporal choices (choosing between rewards available at different points in time) requires determining and comparing the subjective values of available rewards. Several studies have found converging evidence identifying the neural systems that encode subjective value in intertemporal choice. However, the neural mechanisms responsible for the process that produces intertemporal decisions on the basis of subjective values have not been investigated. Using model-based and connectivity analyses of functional magnetic resonance imaging data, we investigated the neural mechanisms underlying the value-accumulation process by which subjective value guides intertemporal decisions. Our results show that the dorsomedial frontal cortex, bilateral posterior parietal cortex, and bilateral lateral prefrontal cortex are all involved in the accumulation of subjective value for the purpose of action selection. Our findings establish a mechanistic framework for understanding frontoparietal contributions to intertemporal choice and suggest that value-accumulation processes in the frontoparietal cortex may be a general mechanism for value-based choice.
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