Associations among physical activity, body mass index, and health-related quality of life by race/ethnicity in a diverse sample of breast cancer survivors.

Associations among physical activity, body mass index, and health-related quality of life by race/ethnicity in a diverse sample of breast cancer survivors.
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各种各样的乳腺癌幸存者样本中,体育锻炼,体重指数和与健康相关的生活质量之间的关联。

DOI:
10.1002/cncr.27389
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发表时间:
2012-08-15
期刊:
影响因子:
6.2
通讯作者:
Pierce JP
Pierce JP
中科院分区:
医学1区
文献类型:
--
作者:
Paxton RJ;Phillips KL;Jones LA;Chang S;Taylor WC;Courneya KS;Pierce JP

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与健康相关的生活质量(HRQOL)、身体质量指数(BMI)和身体活动(PA)水平都与乳腺癌后的预后有关,并可能部分解释某些种族/民族亚群中乳腺癌死亡率较高的原因。在这项研究中,我们在乳腺癌幸存者样本中按种族检查了PA、BMI和HRQOL之间的关系。在基线时评估参加女性健康饮食和生活研究的女性(N=3013, 13%非白人)的PA、BMI、HRQOL以及人口统计学和医学特征。协方差分析用于检验PA和肥胖与HRQOL结果之间的关系。统计检验是双侧的。非裔美国女性比其他种族的女性更不容易达到PA的标准,更容易肥胖(P < 0.05)。在调整后的模型中,无论种族/民族如何,符合PA指南的女性报告的身体健康综合得分(点数差异从10.5到21.2分,均P <0.05)和活力得分(点数差异从9.9到16.5分,均P <0.05)均显著高于未符合PA指南的女性。肥胖和HRQOL之间的联系是混合的,亚裔美国人和非裔美国女性的联系较少,而白人的联系更强。来自不同种族和民族人群的乳腺癌幸存者的PA水平较低,肥胖率较高,这通常与较差的HRQOL相关。文化敏感性PA和减肥干预可以改善这些生活方式特征,从而改善HRQOL。
Health-related quality of life (HRQOL), body mass index (BMI), and physical activity (PA) levels have all been associated with prognosis following breast cancer and may partially explain higher mortality for breast cancer in certain race/ethnic sub-groups. In this study, we examined associations between PA, BMI, and HRQOL by race in a sample of breast cancer survivors. Measures of PA, BMI, and HRQOL as well as demographic and medical characteristics of women (N=3013, 13% nonwhite) who participated in the Women’s Healthy Eating and Living Study were assessed at baseline. Analysis of covariance was used to examine the relationship between PA and obesity with HRQOL outcomes. Statistical tests were two-sided. African-American women were less likely to meet guidelines for PA and more likely to be obese than women from other ethnic groups (P < 0.05). In adjusted models, women who met guidelines for PA reported significantly higher physical health composite (point differences ranged from 10.5 to 21.2 points, all P <0.05) and vitality (point differences ranged from 9.9 to 16.5 points, all P <0.05) scores than those who did not, regardless of race/ethnicity. Associations between obesity and HRQOL were mixed with fewer associations for Asian-American and African-American women and stronger associations for whites. Breast cancer survivors from racially and ethnically diverse populations have lower levels of PA and higher rates of obesity that are generally associated with poorer HRQOL. Culturally sensitive PA and weight loss interventions may improve these lifestyle characteristics and result in improved HRQOL.
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影响因子: 3.7
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发表时间: 2011-03
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影响因子: --
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影响因子: 45.3
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