RBM15 and MKL1 mutational screening in megakaryoblastic leukemia cell lines and clinical samples.

RBM15 and MKL1 mutational screening in megakaryoblastic leukemia cell lines and clinical samples.
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巨核细胞白血病细胞系和临床样本中的 RBM15 和 MKL1 突变筛查。

DOI:
10.1038/sj.leu.2403812
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发表时间:
2005
期刊:
影响因子:
11.4
通讯作者:
Morris,SW
Morris,SW
中科院分区:
医学1区
文献类型:
--
作者:
Kawaguchi,H;Hitzler,JK;Ma,Z;Morris,SW

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1 Shanafelt TD, Geyer SM, Kay NE. Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL. Blood 2004; 103: 1202–1210. 2 Lane BS, Mensah AA, Lin K, Pettitt AR, Sherrington PD. Analysis of V (H) gene sequences using two web-based immunogenetics resources gives different results, but the affinity maturation status of chronic lymphocytic leukaemia clones as assessed from either of the resulting data sets has no prognostic significance. Leukemia 2005,[E-pub ahead of print].3 Dorner T, Foster SJ, Brezinschek HP, Lipsky PE. Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements. Immunol Rev 1998; 162: 161–171. 4 Degan M, Bomben R, Bo MD, Zucchetto A, Nanni P, Rupolo M et al. Analysis of IgV gene mutations in B cell chronic lymphocytic leukaemia according to antigen-driven selection identifies subgroups with different prognosis and usage of the canonical somatic hypermutation machinery. Br J Haematol 2004; 126: 29–42. 5 Gurrieri C, McGuire P, Zan H, Yan XJ, Cerutti A, Albesiano E et al. Chronic lymphocytic leukemia B cells undergo somatic hypermutation and intraclonal immunoglobulin VHDJH gene diversification.
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