MicroRNA (miRNA) in cancer.
MicroRNA (miRNA) in cancer.
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DOI:
10.1186/s12935-015-0185-1
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发表时间:
2015
影响因子:
5.8
通讯作者:
Reddy KB
中科院分区:
文献类型:
--
作者:
Reddy KB
In recent years, there has been a tremendous and growing interest among researchers to investigate the role of mircoRNA (miRNA) in normal cellular as well as in disease processes. miRNAs are a family of small non-coding RNAs which were reported to regulate the expression of various oncogenes or tumor suppressor genes. The expression profiling of miRNAs has already entered into cancer clinics as diagnostic and prognostic biomarkers to assess tumor initiation, progression and response to treatment in cancer patients. This review summarizes: (i) the current understanding of interactions between miRNAs and their target genes, (ii) recent advances in the regulatory mechanisms that control the expression of genes related to carcinogenesis, and (iii) the role of miRNAs in cancer diagnosis and therapy.
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影响因子:
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作者:
Bruce JP;Hui AB;Shi W;Perez-Ordonez B;Weinreb I;Xu W;Haibe-Kains B;Waggott DM;Boutros PC;O'Sullivan B;Waldron J;Huang SH;Chen EX;Gilbert R;Liu FF
通讯作者:
Liu FF
DOI:
10.1038/nrm3679
发表时间:
2013-11
期刊:
Nature reviews. Molecular cell biology
影响因子:
--
作者:
Geisler S;Coller J
通讯作者:
Coller J
影响因子:
--
作者:
Ben-Hamo R;Efroni S
通讯作者:
Efroni S
影响因子:
8.8
作者:
Bryant, R. J.;Pawlowski, T.;Catto, J. W. F.;Marsden, G.;Vessella, R. L.;Rhees, B.;Kuslich, C.;Visakorpi, T.;Hamdy, F. C.
通讯作者:
Hamdy, F. C.
影响因子:
64.8
作者:
Denli, AM;Tops, BBJ;Hannon, GJ
通讯作者:
Hannon, GJ