A survey of modulation of gut microbiota by dietary polyphenols.
A survey of modulation of gut microbiota by dietary polyphenols.
复制标题
DOI：
10.1155/2015/850902
复制
发表时间：
2015
影响因子：
--
通讯作者：
Bartolomé B
中科院分区：
文献类型：
--
作者：
Dueñas M;Muñoz-González I;Cueva C;Jiménez-Girón A;Sánchez-Patán F;Santos-Buelga C;Moreno-Arribas MV;Bartolomé B
膳食多酚存在于广泛的植物食品中，与有益健康有关。该综述旨在从实验方法的角度更新有关饮食中酚类化合物对肠道微生物区系调节的最新信息。在介绍了肠道微生物区系和膳食多酚的一般情况后，按实验设计介绍了与这一主题相关的研究：分批培养发酵、胃肠道模拟器、动物模型研究和人类干预研究。总的来说，研究证据表明，饮食多酚可能通过刺激有益细菌(即乳杆菌和双歧杆菌)的生长和抑制病原菌的生长来维持肠道微生物平衡，从而发挥益生菌的作用，从而有助于维持肠道健康。体外和体内模型的结合可以帮助理解多酚-微生物群-宿主三角的潜在机制，并阐明多酚对人类健康的影响。从技术角度来看，补充富含多酚的物质(酚类提取物、富含酚类的部分等)这可能是改善功能性食品(如乳制品发酵食品)的健康益处的有效选择。
Dietary polyphenols present in a broad range of plant foods have been related to beneficial health effects. This review aims to update the current information about the modulation of the gut microbiota by dietary phenolic compounds, from a perspective based on the experimental approaches used. After referring to general aspects of gut microbiota and dietary polyphenols, studies related to this topic are presented according to their experimental design: batch culture fermentations, gastrointestinal simulators, animal model studies, and human intervention studies. In general, studies evidence that dietary polyphenols may contribute to the maintenance of intestinal health by preserving the gut microbial balance through the stimulation of the growth of beneficial bacteria (i.e., lactobacilli and bifidobacteria) and the inhibition of pathogenic bacteria, exerting prebiotic-like effects. Combination of in vitro and in vivo models could help to understand the underlying mechanisms in the polyphenols-microbiota-host triangle and elucidate the implications of polyphenols on human health. From a technological point of view, supplementation with rich-polyphenolic stuffs (phenolic extracts, phenolic-enriched fractions, etc.) could be an effective option to improve health benefits of functional foods such as the case of dairy fermented foods.
登录
查看更多内容
影响因子：
64.8
作者：
Arumugam, Manimozhiyan;Raes, Jeroen;Pelletier, Eric;Le Paslier, Denis;Yamada, Takuji;Mende, Daniel R.;Fernandes, Gabriel R.;Tap, Julien;Bruls, Thomas;Batto, Jean-Michel;Bertalan, Marcelo;Borruel, Natalia;Casellas, Francesc;Fernandez, Leyden;Gautier, Laurent;Hansen, Torben;Hattori, Masahira;Hayashi, Tetsuya;Kleerebezem, Michiel;Kurokawa, Ken;Leclerc, Marion;Levenez, Florence;Manichanh, Chaysavanh;Nielsen, H. Bjorn;Nielsen, Trine;Pons, Nicolas;Poulain, Julie;Qin, Junjie;Sicheritz-Ponten, Thomas;Tims, Sebastian;Torrents, David;Ugarte, Edgardo;Zoetendal, Erwin G.;Wang, Jun;Guarner, Francisco;Pedersen, Oluf;de Vos, Willem M.;Brunak, Soren;Dore, Joel;Weissenbach, Jean;Ehrlich, S. Dusko;Bork, Peer
通讯作者：
Bork, Peer
影响因子：
6.1
作者：
Gill, Chris I. R.;McDougall, Gorpon J.;Rowland, Ian R.
通讯作者：
Rowland, Ian R.
影响因子：
6.1
作者：
Guglielmetti, Simone;Fracassetti, Daniela;Porrini, Marisa
通讯作者：
Porrini, Marisa
DOI：
10.1016/j.mrfmmm.2005.04.022
发表时间：
2005-12-11
影响因子：
2.3
作者：
Dolara, P;Luceri, C;Cresci, A
通讯作者：
Cresci, A
影响因子：
7.1
作者：
Arts, ICW;Hollman, PCH
通讯作者：
Hollman, PCH