Neuropeptide Control of Feeding Behavior in Birds and Its Difference with Mammals.

Neuropeptide Control of Feeding Behavior in Birds and Its Difference with Mammals.
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DOI:
10.3389/fnins.2016.00485
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发表时间:
2016
影响因子:
4.3
通讯作者:
Tsutsui K
Tsutsui K
中科院分区:
医学2区
文献类型:
--
作者:
Tachibana T;Tsutsui K

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摄食是动物维持生命的基本行为。在过去的几十年里,许多神经肽调节摄食行为已被确定在脊椎动物。这些神经肽被称为“摄食调节神经肽”。关于摄食调节神经肽在脊椎动物包括鸟类中的作用已经有许多研究。一些摄食调节神经肽对鸟类和其他脊椎动物,特别是哺乳动物的摄食行为有不同的影响。不同之处在于食欲神经肽。例如,黑色素浓缩激素、食欲素和胃动素被认为是哺乳动物的食欲神经肽,但对鸟类的摄食行为没有影响。此外,生长激素释放肽和生长激素释放激素,也被称为哺乳动物的食欲神经肽,抑制鸟类的摄食行为。因此,在脊椎动物的进化过程中,摄食调节机制可能发生了变化。本文综述了肽能摄食调节因子在鸟类中的作用,并讨论了它们在鸟类和其他脊椎动物中作用的差异。
Feeding is an essential behavior for animals to sustain their lives. Over the past several decades, many neuropeptides that regulate feeding behavior have been identified in vertebrates. These neuropeptides are called “feeding regulatory neuropeptides.” There have been numerous studies on the role of feeding regulatory neuropeptides in vertebrates including birds. Some feeding regulatory neuropeptides show different effects on feeding behavior between birds and other vertebrates, particularly mammals. The difference is marked with orexigenic neuropeptides. For example, melanin-concentrating hormone, orexin, and motilin, which are regarded as orexigenic neuropeptides in mammals, have no effect on feeding behavior in birds. Furthermore, ghrelin and growth hormone-releasing hormone, which are also known as orexigenic neuropeptides in mammals, suppress feeding behavior in birds. Thus, it is likely that the feeding regulatory mechanism has changed during the evolution of vertebrates. This review summarizes the recent knowledge of peptidergic feeding regulatory factors in birds and discusses the difference in their action between birds and other vertebrates.
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