Role of the anterior insular cortex in integrative causal signaling during multisensory auditory-visual attention.
Role of the anterior insular cortex in integrative causal signaling during multisensory auditory-visual attention.
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DOI：
10.1111/ejn.12764
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发表时间：
2015-01
期刊：
影响因子：
--
通讯作者：
Menon V
中科院分区：
文献类型：
--
作者：
Chen T;Michels L;Supekar K;Kochalka J;Ryali S;Menon V
对来自多个感官的信息的协调注意是我们对显著环境事件做出反应的能力的基础，但对引导来自多个感官的信息整合的大脑网络机制知之甚少。在这里，我们调查的动态因果机制的基础上多感官视觉注意，专注于网络的右半球额叶扣带顶叶区域牵连在广泛的任务，涉及注意力和认知控制。参与者在功能磁共振成像扫描过程中进行了三个“古怪”的注意力任务，涉及听觉，视觉和多感官视觉刺激。我们发现，右前额叶（rAI）表现出最显着的因果关系影响所有其他额叶扣带回顶叶区域，作为一个主要的因果控制枢纽在多感官注意。至关重要的是，我们然后测试了两个竞争模型的作用，rAI在多感官注意：一个“集成”的信号模型，其中的rAI产生一个共同的多感官控制信号与同时注意到听觉和视觉古怪的刺激与“隔离”的信号模型，其中的rAI产生两个隔离和独立的信号，在每一个感官模态。我们发现了对整合而不是隔离的信号模式的强烈支持。此外，来自rAI的综合控制信号的强度在背侧前扣带皮层和后顶叶皮层上最明显，这两个关键节点分别是显着性和中央执行网络。这些结果保留了额外的上级颞沟区参与多感觉处理。我们的研究为人工智能促进多感官注意的动态因果机制提供了新的见解。
Coordinated attention to information from multiple senses is fundamental to our ability to respond to salient environmental events, yet little is known about brain network mechanisms that guide integration of information from multiple senses. Here we investigate dynamic causal mechanisms underlying multisensory auditory–visual attention, focusing on a network of right-hemisphere frontal–cingulate–parietal regions implicated in a wide range of tasks involving attention and cognitive control. Participants performed three ‘oddball’ attention tasks involving auditory, visual and multisensory auditory–visual stimuli during fMRI scanning. We found that the right anterior insula (rAI) demonstrated the most significant causal influences on all other frontal–cingulate–parietal regions, serving as a major causal control hub during multisensory attention. Crucially, we then tested two competing models of the role of the rAI in multisensory attention: an ‘integrated’ signaling model in which the rAI generates a common multisensory control signal associated with simultaneous attention to auditory and visual oddball stimuli versus a ‘segregated’ signaling model in which the rAI generates two segregated and independent signals in each sensory modality. We found strong support for the integrated, rather than the segregated, signaling model. Furthermore, the strength of the integrated control signal from the rAI was most pronounced on the dorsal anterior cingulate and posterior parietal cortices, two key nodes of saliency and central executive networks respectively. These results were preserved with the addition of a superior temporal sulcus region involved in multisensory processing. Our study provides new insights into the dynamic causal mechanisms by which the AI facilitates multisensory attention.
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DOI：
10.1098/rstb.2005.1634
发表时间：
2005-05-29
影响因子：
6.3
作者：
Beckmann, CF;DeLuca, M;Smith, SM
通讯作者：
Smith, SM
影响因子：
5.7
作者：
FRISTON, KJ;HOLMES, AP;TURNER, R
通讯作者：
TURNER, R
影响因子：
9.2
作者：
Calvert, GA;Campbell, R;Brammer, MJ
通讯作者：
Brammer, MJ
影响因子：
3.1
作者：
Menon, Vinod;Uddin, Lucina Q.
通讯作者：
Uddin, Lucina Q.
影响因子：
5.3
作者：
Bushara, KO;Grafman, J;Hallett, M
通讯作者：
Hallett, M