Genetic influences on the association between personality risk factors and alcohol use and abuse.

Genetic influences on the association between personality risk factors and alcohol use and abuse.
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遗传对人格危险因素与饮酒和滥用之间关联的影响。

DOI:
10.1037/0021-843x.112.2.282
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发表时间:
2003
影响因子:
4.6
通讯作者:
Rose,RichardJ
Rose,RichardJ
中科院分区:
心理学1区
文献类型:
--
作者:
Mustanski,BrianS;Viken,RichardJ;Kaprio,Jaakko;Rose,RichardJ

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作者评估了1,320对18.5岁时一致报告不戒酒的双胞胎的2个人格维度与使用和滥用酒精的关系。2酒精的结果差异与2个人格维度:酒精相关的问题与社会越轨行为的相关性更高,而不是与寻求刺激(ES),酒精消费与ES的相关性更高,而不是社会越轨行为。与数据拟合的生物统计学模型在遗传协方差中发现了类似的模式,尽管社会偏差和酒精结果之间的遗传相关性比ES之间的差异更明显。研究结果表明,遗传影响的基础上的个性与酒精的使用和随后的问题,并说明实用信息的双胞胎分析,探索基因,个性和行为障碍之间的联系。
The authors assessed the association of 2 personality dimensions with use and abuse of alcohol in 1,320 twin pairs concordantly reporting nonabstinence at age 18.5 years. The 2 alcohol outcomes differentially relate to the 2 personality dimensions: Alcohol-related problems correlate more highly with social deviance than with excitement seeking (ES), and alcohol consumption correlates more highly with ES than with social deviance. Biometric models fit to the data identified similar patterns in genetic covariance, although differences were more evident in genetic correlations between social deviance and alcohol outcomes than in those for ES. Results suggest that genetic influences underlie the association of personality with alcohol use and subsequent problems and illustrate the utility of informative twin analyses in exploring links between genes, personality, and behavior disorder.
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期刊: SCIENCE
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