GuPPy, a Python toolbox for the analysis of fiber photometry data.

GuPPy, a Python toolbox for the analysis of fiber photometry data.
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DOI:
10.1038/s41598-021-03626-9
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发表时间:
2021-12-20
期刊:
影响因子:
4.6
通讯作者:
Lerner TN
Lerner TN
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Sherathiya VN;Schaid MD;Seiler JL;Lopez GC;Lerner TN

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纤维光度法(FP)是一种适用于记录自由行为动物体内神经活动的方法。由于其易于使用、成本低、能够将联合收割机FP与自由运动行为结合以及其他优点,它已成为神经科学中的流行工具。然而,FP数据的分析对于新用户来说可能是一个挑战,特别是那些编程背景有限的用户。在这里,我们介绍了Python中的Guided Photometry Analysis(GuPPy),这是一个免费的开源FP分析工具。GuPPy被设计为跨计算平台运行,可以接受来自各种FP数据采集系统的数据。该程序为用户提供一组图形用户界面(GUI)来加载数据和提供输入参数。生成的图表可以很容易地导出,以集成到科学数字中。作为一个开源工具,GuPPy可以由具有Python知识的用户修改以满足他们的特定需求。
Fiber photometry (FP) is an adaptable method for recording in vivo neural activity in freely behaving animals. It has become a popular tool in neuroscience due to its ease of use, low cost, the ability to combine FP with freely moving behavior, among other advantages. However, analysis of FP data can be challenging for new users, especially those with a limited programming background. Here, we present Guided Photometry Analysis in Python (GuPPy), a free and open-source FP analysis tool. GuPPy is designed to operate across computing platforms and can accept data from a variety of FP data acquisition systems. The program presents users with a set of graphic user interfaces (GUIs) to load data and provide input parameters. Graphs are produced that can be easily exported for integration into scientific figures. As an open-source tool, GuPPy can be modified by users with knowledge of Python to fit their specific needs.
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