The Correlation Between RDW, MPV and Weight Indices After Metabolic Surgery in Patients with Obesity and DM/IGR: Follow-Up Observation at 12 Months.
The Correlation Between RDW, MPV and Weight Indices After Metabolic Surgery in Patients with Obesity and DM/IGR: Follow-Up Observation at 12 Months.
复制标题
肥胖与DM/IGR患者代谢手术后RDW、MPV和体重指数的相关性：12个月随访观察
DOI：
10.1007/s13300-020-00897-9
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发表时间：
2020-10
期刊：
影响因子：
--
通讯作者：
Zhou H
中科院分区：
文献类型：
--
作者：
Zhou L;Lin S;Zhang F;Ma Y;Fu Z;Gong Y;Hu D;Ma S;Ye X;Qian L;Geng X;Yang N;Liang H;Zhou H
简介红细胞分布宽度（RDW）和平均血小板体积（MPV）都是许多疾病预后的新生物标志物。本研究旨在观察RDW和MPV对肥胖合并糖代谢异常[糖尿病或血糖调节受损(DM/IGR)]患者不同代谢手术后体重减轻的预测价值。方法回顾性分析98例接受Roux-en-Y胃绕道术(RYGB)或袖状胃切除术(SG)的肥胖合并DM/IGR患者的体重(BW)、体重指数(BMI)和血常规指数。术后1个月两组RDW、MPV均较术前显着升高，随后逐渐下降。术后12个月，RYGB组的RDW水平显着低于术前。在RYGB组中，高水平体重减轻百分比（%BW）（≥31.90）的患者在术后6个月和12个月时的RDW水平较相应低水平的患者显着下降。术前高水平RDW（≥ 12.90）组的%BW以及术后6个月和12个月的BW和BMI变化（ΔBW和ΔBMI）显着高于低水平RYGB组。两组其他随访时间点术前MPV高低水平均无明显体重指数差异。结论术前基线RDW和术后RDW水平可以初步预测肥胖合并DM/IGR患者不同代谢手术的效果。
IntroductionRed blood cell distribution width (RDW) and mean platelet volume (MPV) are both new biomarkers for the prognosis of many diseases. This study aimed to observe the predictive values of RDW and MPV for weight loss after different metabolic surgeries in patients with obesity and abnormal glucose metabolism [diabetes mellitus or impaired glucose regulation (DM/IGR)].MethodsWe retrospectively analyzed the body weight (BW), body mass index (BMI) and blood routine index of 98 patients with obesity and DM/IGR who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG).ResultsLevels of RDW and MPV in both groups were significantly higher than before 1 month after surgery and then gradually decreased. Twelve months after surgery, the RDW level in the RYGB group was significantly lower than that before surgery. In the RYGB group, the RDW level of patients in the high-level percentage weight loss (%BW) (≥ 31.90) at 6 and 12 months after surgery decreased significantly compared to those in the corresponding low level. %BW and change in BW and BMI (ΔBW and ΔBMI) at 6 and 12 months after surgery in the high-level RDW (≥ 12.90) before surgery were significantly higher than those in the low level in the RYGB group. No significant difference in weight index was found in the high and low levels of the MPV before surgery in either group at other follow-up time points.ConclusionsPreoperative baseline RDW and postoperative RDW levels can preliminarily predict the effect of different metabolic surgeries in patients with obesity and DM/IGR.
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影响因子：
1.2
作者：
Gang, Li;Wan Lifang
通讯作者：
Wan Lifang
DOI：
10.1016/j.dsx.2016.12.021
发表时间：
2017-11-01
影响因子：
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作者：
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DOI：
10.1007/s00464-016-4798-9
发表时间：
2016-10
期刊：
Surgical endoscopy
影响因子：
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通讯作者：
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