Testing covariance models for MEG source reconstruction of hippocampal activity.
Testing covariance models for MEG source reconstruction of hippocampal activity.
复制标题
测试海马活动的MEG源重建的协方差模型。
DOI:
10.1038/s41598-021-96933-0
复制
发表时间:
2021-09-02
影响因子:
4.6
通讯作者:
Barnes GR
中科院分区:
文献类型:
--
作者:
O'Neill GC;Barry DN;Tierney TM;Mellor S;Maguire EA;Barnes GR
Beamforming is one of the most commonly used source reconstruction methods for magneto- and electroencephalography (M/EEG). One underlying assumption, however, is that distant sources are uncorrelated and here we tested whether this is an appropriate model for the human hippocampal data. We revised the Empirical Bayesian Beamfomer (EBB) to accommodate specific a-priori correlated source models. We showed in simulation that we could use model evidence (as approximated by Free Energy) to distinguish between different correlated and uncorrelated source scenarios. Using group MEG data in which the participants performed a hippocampal-dependent task, we explored the possibility that the hippocampus or the cortex or both were correlated in their activity across hemispheres. We found that incorporating a correlated hippocampal source model significantly improved model evidence. Our findings help to explain why, up until now, the majority of MEG-reported hippocampal activity (typically making use of beamformers) has been estimated as unilateral.
登录
查看更多内容
影响因子:
5.7
作者:
Barry, Daniel N.;Tierney, Tim M.;Maguire, Eleanor A.
通讯作者:
Maguire, Eleanor A.
DOI:
10.1523/jneurosci.4549-07.2007
发表时间:
2007-12-26
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Hassabis D;Kumaran D;Maguire EA
通讯作者:
Maguire EA
影响因子:
5.7
作者:
Henson, R. N.;Mattout, J.;Friston, K. J.
通讯作者:
Friston, K. J.
影响因子:
16.6
作者:
Goyal, Abhinav;Miller, Jonathan;Jacobs, Joshua
通讯作者:
Jacobs, Joshua
影响因子:
5.7
作者:
Friston, Karl J.;Harrison, Lee;Mattout, Jeremie
通讯作者:
Mattout, Jeremie