Electrohydrodynamic atomization: A two-decade effort to produce and process micro-/nanoparticulate materials.

Electrohydrodynamic atomization: A two-decade effort to produce and process micro-/nanoparticulate materials.
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DOI:
10.1016/j.ces.2014.08.061
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发表时间:
2015-03-24
影响因子:
4.7
通讯作者:
Wang CH
Wang CH
中科院分区:
工程技术2区
文献类型:
--
作者:
Xie J;Jiang J;Davoodi P;Srinivasan MP;Wang CH

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电流体动力雾化(EHDA)技术,又称电喷雾技术,已经被研究了一个多世纪。然而,自20世纪90年代以来,它已开始用于生产和加工微/纳米结构材料。由于EHDA实验装置的简单和灵活,它已成功地用于生成具有可控成分、结构、尺寸、形态和形状的颗粒材料。EHDA也被用于以良好控制的方式在表面上沉积微颗粒和纳米颗粒材料。所有这些特性使EHDA成为制备和组装各种微纳米结构材料的迷人工具,这些材料已被用于制药、食品和医疗保健等领域。我们的目标是回顾这一领域,这使科学家和工程师能够了解EHDA技术,以及如何使用它来创建、加工和组装具有独特和有趣特性的微/纳米颗粒材料。我们首先简要介绍EHDA技术的原理和设置。然后讨论了成功应用EHDA技术的关键问题,包括颗粒材料的组成、尺寸、形状、形态、结构及其组装的控制。我们还举例说明了颗粒材料的许多潜在应用,特别是在药物输送和再生医学领域。接下来,我们回顾了单喷嘴和同轴喷嘴泰勒锥射流形成的仿真和建模。提出了粒子传输和沉积的数学模型,以便更深入地了解制备,收集和图像化过程中的有效参数。最后,我们对该领域的前景和未来可能性进行了讨论。
Electrohydrodynamic atomization (EHDA), also called electrospray technique, has been studied for more than one century. However, since 1990s it has begun to be used to produce and process micro-/nanostructured materials. Owing to the simplicity and flexibility in EHDA experimental setup, it has been successfully employed to generate particulate materials with controllable compositions, structures, sizes, morphologies, and shapes. EHDA has also been used to deposit micro- and nanoparticulate materials on surfaces in a well-controlled manner. All these attributes make EHDA a fascinating tool for preparing and assembling a wide range of micro- and nanostructured materials which have been exploited for use in pharmaceutics, food, and healthcare to name a few. Our goal is to review this field, which allows scientists and engineers to learn about the EHDA technique and how it might be used to create, process, and assemble micro-/nanoparticulate materials with unique and intriguing properties. We begin with a brief introduction to the mechanism and setup of EHDA technique. We then discuss issues critical to successful application of EHDA technique, including control of composition, size, shape, morphology, structure of particulate materials and their assembly. We also illustrate a few of the many potential applications of particulate materials, especially in the area of drug delivery and regenerative medicine. Next, we review the simulation and modeling of Taylor cone-jet formation for a single and co-axial nozzle. The mathematical modeling of particle transport and deposition is presented to provide a deeper understanding of the effective parameters in the preparation, collection and pattering processes. We conclude this article with a discussion on perspectives and future possibilities in this field.
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