Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention.
Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention.
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DOI：
10.1080/07853890.2022.2067352
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发表时间：
2022-12
影响因子：
4.4
通讯作者：
中科院分区：
文献类型：
--
作者：
为了了解过度肥胖对心脏代谢性疾病风险的有害性质，必须准确地估计全身脂肪百分比(%FAT)。成本和可获得性往往阻碍了先进成像方法的使用，如双能X射线吸收法(DXA)和磁共振成像(MRI)。相对脂肪质量(RFM)是一种新兴的基于腰围、身高和生物性别的全身脂肪百分比估计器。这项辅助研究的目的是在社区居住的肥胖老年人中检查RFM和肥胖的黄金标准之间的关系，并评估RFM的变化是否反映了经过12个月的生活方式干预后脂肪百分比的变化(Clinicaltrials.gov#NCT00955903)。受试者(N = 163人，男性37.4%，年龄70.3 ± 4.7 )随机分为单纯运动组、运动 + 营养密集型体重维持组、运动 + 营养密集型能量限制500kcal/d组。在基线和12个 月时，通过DXA和核磁共振以及人体测量学评估总的和局部的肥胖。基线时RFM与DXA全身脂肪百分比和DXA躯干脂肪百分比呈显著正相关。等效性检验表明，仅对女性而言，RFM被认为等同于DXA全身脂肪百分比。此外，从基线到12个 月，仅在运动 + 能量限制组的女性参与者中观察到RFM显著减少。RFM的变化与MRI测定的DXA全身脂肪百分比、DXA躯干脂肪和总腹部脂肪组织的变化显著相关。相对脂肪质量(RFM)是一种新兴的基于腰围、身高和生物性别的全身脂肪百分比估计指标，它被有意开发为一种简单的肥胖估计，克服了身体质量指数等测量方法的局限性。在目前的研究中，相关性和一致性分析的结果支持使用RFM来估计社区居住的肥胖老年人口的全身脂肪百分比，而先进的方法，即双能X射线吸收法，是不可行的。在12个月的时间里也观察到RFM的显著减少，这与全身脂肪百分比的变化显著相关；因此，支持RFM对生活方式变化的敏感性。结果支持在先进的成像技术不可行的情况下，使用RFM作为全身脂肪百分比的估计。此外，结果表明，在肥胖的老年女性中，这一指数对12个 月内脂肪质量的变化很敏感。
It is imperative to accurately estimate whole body fat percentage (%fat) to understand the deleterious nature of excess adiposity on cardiometabolic disease risk. Cost and accessibility often preclude the use of advanced imaging methods like dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI). Relative fat mass (RFM) is an emerging estimator of whole body %fat based on waist circumference, height, and biological sex. The purpose of this ancillary study was to examine the relationship between RFM and gold-standard measures of adiposity among community-dwelling older adults with obesity and to evaluate if changes in RFM reflect changes in %fat following a 12-month lifestyle intervention (clinicaltrials.gov #NCT00955903). Participants (N = 163, 37.4% male, 70.3 ± 4.7 years) were randomized to the exercise only group, exercise + nutrient-dense weight maintenance group, or exercise + nutrient-dense energy restriction of 500 kcal/d group. Total and regional adiposity assessed by DXA and MRI, as well as anthropometrics, were evaluated at baseline and 12 months. RFM was significantly positively correlated with DXA whole body %fat and DXA trunk %fat at baseline. Equivalence testing revealed that RFM was considered equivalent to DXA whole body %fat for females only. Additionally, from baseline to 12 months, a significant reduction in RFM was observed among female participants in the exercise + energy restriction group only. Changes in RFM were significantly correlated with changes in DXA whole body %fat, DXA trunk fat, and total abdominal fat tissue determined by MRI. Relative fat mass (RFM), an emerging estimator of whole body %fat based on waist circumference, height, and biological sex, was intentionally developed to be a simple estimate of adiposity that overcomes limitations of measures like body mass index. In the current study, results from correlations and agreement analyses support the use of RFM to estimate whole-body fat percentage in a community-dwelling older adult population with obesity when advanced methods, namely dual-energy X-ray absorptiometry, are not feasible. Significant reductions in RFM were also observed over a 12-month period that was significantly correlated with changes in whole body fat percentage; thus, supporting the sensitivity of RFM to lifestyle changes. Results support the use of RFM as an estimate of whole body %fat where advanced imaging techniques are not feasible. Furthermore, results suggest that this index is sensitive to changes in fat mass over 12 months in female older adults with obesity.
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影响因子：
3.3
作者：
Giavarina D
通讯作者：
Giavarina D
影响因子：
2.5
作者：
Hayes, Burton L.;Curtis, Jeffrey R.;Carbone, Laura D.
通讯作者：
Carbone, Laura D.
影响因子：
4.6
作者：
Woolcott, Orison O.;Bergman, Richard N.
通讯作者：
Bergman, Richard N.
DOI：
10.1093/gerona/glw237
发表时间：
2018-01-01
影响因子：
5.1
作者：
Ard, Jamy D.;Gower, Barbara;Locher, Julie L.
通讯作者：
Locher, Julie L.
影响因子：
3
作者：
Correa, Cinthia Rejane;Formolo, Natalia Paludo Silveira;Nunes, Everson Araujo
通讯作者：
Nunes, Everson Araujo