Genome demethylation and imprinting in the endosperm.
Genome demethylation and imprinting in the endosperm.
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DOI:
10.1016/j.pbi.2011.02.006
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发表时间:
2011-04
影响因子:
9.5
通讯作者:
Fischer RL
中科院分区:
文献类型:
--
作者:
Bauer MJ;Fischer RL
Imprinting occurs in the endosperm of flowering plants. The endosperm, a product of central cell fertilization, is critical for embryo and seed development. Imprinting in the endosperm is mainly due to the inherited differences in gamete epigenetic composition. Studies have also shown that there are differences in genomic DNA methylation patterns between embryo and endosperm. Examining those differences, along with mutations in the DNA demethylase gene DEMETER, gives insight into the number of imprinted genes and how an antagonistic relationship between TE defense and gene regulation could evolutionarily affect imprinting establishment. Finally, studies demonstrate that DEMETER demethylase activity influences endosperm chromatin composition, and could possibly enhance DNA de novo methylation activity.
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