Applications of chitin and its derivatives in biological medicine.
Applications of chitin and its derivatives in biological medicine.
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DOI：
10.3390/ijms11125152
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发表时间：
2010
影响因子：
5.6
通讯作者：
Kim MM
中科院分区：
文献类型：
--
作者：
Park BK;Kim MM
Chitin and its derivatives—as a potential resource as well as multiple functional substrates—have generated attractive interest in various fields such as biomedical, pharmaceutical, food and environmental industries, since the first isolation of chitin in 1811. Moreover, chitosan and its chitooligosaccharides (COS) are degraded products of chitin through enzymatic and acidic hydrolysis processes; and COS, in particular, is well suited for potential biological application, due to the biocompatibility and nontoxic nature of chitosan. In this review, we investigate the current bioactivities of chitin derivatives, which are all correlated with their biomedical properties. Several new and cutting edge insights here may provide a molecular basis for the mechanism of chitin, and hence may aid its use for medical and pharmaceutical applications.
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影响因子：
6.1
作者：
Je, Jae-Young;Kim, Se-Kwon
通讯作者：
Kim, Se-Kwon
影响因子：
4.4
作者：
Da Silva, Carla A.;Chalouni, Cecile;Elias, Jack A.
通讯作者：
Elias, Jack A.
影响因子：
10.8
作者：
Janes, KA;Fresneau, MP;Alonso, MJ
通讯作者：
Alonso, MJ
影响因子：
5.8
作者：
De Campos, AM;Sánchez, A;Alonso, MJ
通讯作者：
Alonso, MJ
影响因子：
14
作者：
Chatelet, C;Damour, O;Domard, A
通讯作者：
Domard, A