Optimization of the laser irradiation pattern in a high frame rate integrated photoacoustic / ultrasound (PAUS) imaging system.
Optimization of the laser irradiation pattern in a high frame rate integrated photoacoustic / ultrasound (PAUS) imaging system.
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DOI：
10.1109/ultsym.2015.0032
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发表时间：
2015-10
期刊：
影响因子：
--
通讯作者：
Pelivanov, Ivan
中科院分区：
文献类型：
--
作者：
Yoon, Soon Joon;Hsieh, Bao-Yu;Wei, Chen-Wei;Nguyen, Thu-Mai;Arnal, Bastien;Pelivanov, Ivan;O'Donnell, Matthew;Pelivanov, Ivan
关键词：
为了将实时光声学(PA)集成到超声(US)扫描仪中，并加快联合PAUS成像的临床应用，我们先前开发了一种系统，该系统使用便携式、低成本、低脉冲能量、高重复频率(~1 kHz)的激光器和1D振镜，用于在成像区域进行快速激光扫描。然而，由于对辐射的规定(1W/cm2)，帧速率和脉冲能量受到限制。因此，需要优化激光扫描方案以在该安全限制内提供高帧速率。此外，激光应该均匀分布，以最大限度地减少扫描方法造成的任何伪影。本文利用三维蒙特卡罗模拟计算了激光的分布，并进一步开发了利用二维振镜扫描器对激光进行水平和横向扫描的系统，以在辐射安全限度内获得更高的帧速率。在鸡的胸部组织中插入一根针来演示我们的优化扫描方案。
To integrate real-time photoacoustics (PA) into ultrasound (US) scanners and accelerate clinical translation of combined PAUS imaging, we previously developed a system using a portable, low-cost, low pulse energy, high-repetition rate laser (~1kHz) with a 1D galvo-mirror for rapid laser beam scanning over the imaging area. However, the frame rate and pulse energy are limited because of regulations on the radiance (1 W/cm2). Therefore, a laser scan scheme needs to be optimized to provide high frame rate within this safety limit. In addition, the laser light should be evenly distributed to minimize any artifacts caused by the scanning approach. In this paper, we calculated the laser light distribution using 3D Monte Carlo simulation and further developed the system to scan the laser beam in elevation as well as laterally using a 2-dimensional galvo-mirror scanner to achieve higher frame rates within the radiance safety limit. Insertion of a needle into chicken breast tissue was used to demonstrate our optimized scan scheme.
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影响因子：
3.6
作者：
Buehler, Andreas;Kacprowicz, Marcin;Ntziachristos, Vasilis
通讯作者：
Ntziachristos, Vasilis
DOI：
10.1016/j.urolonc.2011.02.014
发表时间：
2011-05
期刊：
Urologic oncology
影响因子：
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作者：
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Li, Chun
影响因子：
3.5
作者：
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通讯作者：
Emelianov, Stanislav