Low birth weight: is it related to assisted reproductive technology or underlying infertility?
Low birth weight: is it related to assisted reproductive technology or underlying infertility?
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DOI：
10.1016/j.fertnstert.2012.12.035
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发表时间：
2013-02
影响因子：
6.7
通讯作者：
Perales-Puchalt A
中科院分区：
文献类型：
--
作者：
Kondapalli LA;Perales-Puchalt A
自1978年以来，我们见证了辅助生殖技术（ART）的成功发展，怀孕率提高，需求不断增长。然而，近年来，由于其对婴儿的潜在健康影响，其安全性越来越受到关注。成人疾病发育起源的提出使低出生体重成为一个重要的健康问题。尽管有多项研究将ART与LBW联系起来，但这种联系的病因在很大程度上仍然未知。本文回顾了ART的不同组成部分与低出生体重不孕症之间的潜在联系，同时承认现有文献解释的局限性。
Since 1978, we have witnessed a successful evolution of assisted reproductive technology (ART), with improvement of the pregnancy rates and a growing demand. However, in recent years, there has been increasing concern regarding its safety due to the potential health impact on its infants. The raise of the developmental origins of adult disease has positioned low birth weight (LBW) as a significant health issue. Despite multiple studies have associated ART with LBW, the etiology of this association remains largely unknown. This paper reviews the potential association between different components of ART and infertility with LBW, while acknowledging the limitations to interpretation of the existing literature.
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