A Compact Multi-Distance DCS and Time Domain NIRS Hybrid System for Hemodynamic and Metabolic Measurements.

A Compact Multi-Distance DCS and Time Domain NIRS Hybrid System for Hemodynamic and Metabolic Measurements.
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DOI:
10.3390/s21030870
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发表时间:
2021-01-28
期刊:
Sensors (Basel, Switzerland)
影响因子:
--
通讯作者:
Torricelli A
Torricelli A
中科院分区:
其他
文献类型:
--
作者:
Amendola C;Lacerenza M;Buttafava M;Tosi A;Spinelli L;Contini D;Torricelli A

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在这项工作中,我们提出了一种新的多距离漫相关光谱(DCS)设备与紧凑的最先进的时域近红外光谱(TD-NIRS)设备集成在一起。混合分布式控制系统和TD-NIRS系统允许检索有关血流、组织氧合和氧代谢率的信息。从稳定性、重复性、恢复扩散系数变化的能力、组织光学性质的影响、不同计数率的影响和深度灵敏度等方面对该装置的性能进行了评估。还对分布式控制系统和TD-NIRS光信号之间的串扰进行了评估。最后,进行了活体实验(手臂上的静脉和动脉袖带闭塞),以测试混合系统测量血流变化的能力。
In this work, we present a new multi-distance diffuse correlation spectroscopy (DCS) device integrated with a compact state-of-the-art time domain near infrared spectroscopy (TD-NIRS) device. The hybrid DCS and TD-NIRS system allows to retrieve information on blood flow, tissue oxygenation, and oxygen metabolic rate. The DCS device performances were estimated in terms of stability, repeatability, ability in retrieving variations of diffusion coefficient, influence of the tissue optical properties, effect of varying count rates and depth sensitivity. Crosstalk between DCS and TD-NIRS optical signals was also evaluated. Finally, in vivo experiments (venous and arterial cuff occlusions on the arm) were conducted to test the ability of the hybrid system in measuring blood flow variations.
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发表时间: 1997-01-01
影响因子: 1.9
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