Debye screening in single-molecule carbon nanotube field-effect sensors.

Debye screening in single-molecule carbon nanotube field-effect sensors.
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在单分子碳纳米管现场效应传感器中进行DEBYE筛选。

DOI:
10.1021/nl201781q
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发表时间:
2011-09-14
期刊:
影响因子:
10.8
通讯作者:
Shepard KL
Shepard KL
中科院分区:
材料科学1区
文献类型:
--
作者:
Sorgenfrei S;Chiu CY;Johnston M;Nuckolls C;Shepard KL

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Point-functionalized carbon nanotube field-effect transistors can serve as highly sensitive detectors for biomolecules. With a probe molecule covalently bound to a defect in the nanotube sidewall, two-level random telegraph noise (RTN) in the conductance of the device is observed as a result of a charged target biomolecule binding and unbinding at the defect site. Charge in proximity to the defect modulates the potential (and transmission) of the conductance-limiting barrier created by the defect. In this Letter, we study how these single-molecule electronic sensors are affected by ionic screening. Both charge in proximity to the defect site and buffer concentration are found to affect RTN amplitude in a manner that follows from simple Debye length considerations. RTN amplitude is also dependent on the potential of the electrolyte gate as applied to the reference electrode; at high enough repulsive potentials, the target DNA is completely repelled and RTN is suppressed.
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