Childhood CBCL bipolar profile and adolescent/young adult personality disorders: a 9-year follow-up.

Childhood CBCL bipolar profile and adolescent/young adult personality disorders: a 9-year follow-up.
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DOI:
10.1016/j.jad.2010.10.019
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发表时间:
2011-04
影响因子:
6.6
通讯作者:
Newcorn, Jeffrey H.
Newcorn, Jeffrey H.
中科院分区:
医学2区
文献类型:
--
作者:
Halperin, Jeffrey M.;Rucklidge, Julia J.;Powers, Robyn L.;Miller, Carlin J.;Newcorn, Jeffrey H.

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评估诊断为ADHD并随访9年的儿童中与阳性儿童行为量表-青少年双相情感障碍表型(CBCL-JBD)相关的青少年后期精神结局。152名被诊断为ADHD的儿童(7-11岁)的父母完成了CBCL。这些家长中有90人在9年后再次完成了这项测试,作为使用半结构化访谈评估的轴I和轴II诊断综合评估的一部分。如前所述,CBCL-JBD表型定义为注意力问题、攻击性和焦虑/抑郁子量表的T评分≥ 70。CBCL-JBD表型在31%的随访者中发现,但只有4.9%的样本在随访时继续符合表型标准。只有两个样本在青春期后期发展为双相情感障碍,其中只有一个在儿童时期具有CBCL-JBD特征。该代理没有预测任何轴I障碍。然而,CBCL-JBD代理是高度预测后来的人格障碍。只有一个亚组的原始儿童样本进行了跟踪。鉴于该样本仅限于ADHD儿童,尚不清楚CBCL评分对人格障碍的预测是否会推广到更广泛的社区或临床人群。儿童期阳性CBCL-JBD表型特征不能预测青春期后期的轴I障碍;然而,它可能是人格障碍出现的预后。
To assess the late adolescent psychiatric outcomes associated with a positive Child Behavior Checklist – Juvenile Bipolar Disorder Phenotype (CBCL-JBD) in children diagnosed with ADHD and followed over a 9-year period. Parents of 152 children diagnosed as ADHD (ages 7–11 years) completed the CBCL. Ninety of these parents completed it again 9 years later as part of a comprehensive evaluation of Axis I and II diagnoses as assessed using semi-structured interviews. As previously proposed, the CBCL-JBD phenotype was defined as T-scores of 70 or greater on the Attention Problems, Aggression, and Anxiety/Depression subscales. The CBCL-JBD phenotype was found in 31% of those followed but only 4.9% of the sample continued to meet the phenotype criteria at follow up. Only two of the sample developed Bipolar Disorder by late adolescence and only one of those had the CBCL-JBD profile in childhood. The proxy did not predict any Axis I disorders. However, the CBCL-JBD proxy was highly predictive of later personality disorders. Only a subgroup of the original childhood sample was followed. Given this sample was confined to children with ADHD, it is not known whether the prediction of personality disorders from CBCL scores would generalize to a wider community or clinical population A positive CBCL-JBD phenotype profile in childhood does not predict Axis I Disorders in late adolescence; however, it may be prognostic of the emergence of personality disorders.
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发表时间: 2003-08-01
影响因子: 11.3
作者:
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影响因子: 7.3
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