Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) Analysis for the Identification of Pathogenic Microorganisms: A Review.
Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) Analysis for the Identification of Pathogenic Microorganisms: A Review.
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基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS)分析鉴定病原微生物:综述。
DOI:
10.3390/microorganisms9071536
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发表时间:
2021-07-19
期刊:
影响因子:
4.5
通讯作者:
Hsueh PR
中科院分区:
文献类型:
--
作者:
Chen XF;Hou X;Xiao M;Zhang L;Cheng JW;Zhou ML;Huang JJ;Zhang JJ;Xu YC;Hsueh PR
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used in the field of clinical microbiology since 2010. Compared with the traditional technique of biochemical identification, MALDI-TOF MS has many advantages, including convenience, speed, accuracy, and low cost. The accuracy and speed of identification using MALDI-TOF MS have been increasing with the development of sample preparation, database enrichment, and algorithm optimization. MALDI-TOF MS has shown promising results in identifying cultured colonies and rapidly detecting samples. MALDI-TOF MS has critical research applications for the rapid detection of highly virulent and drug-resistant pathogens. Here we present a scientific review that evaluates the performance of MALDI-TOF MS in identifying clinical pathogenic microorganisms. MALDI-TOF MS is a promising tool in identifying clinical microorganisms, although some aspects still require improvement.
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影响因子:
3.7
作者:
Chao QT;Lee TF;Teng SH;Peng LY;Chen PH;Teng LJ;Hsueh PR
通讯作者:
Hsueh PR
DOI:
10.3390/pathogens10030366
发表时间:
2021-03-18
期刊:
Pathogens (Basel, Switzerland)
影响因子:
--
作者:
Berlamont H;De Witte C;De Bruyckere S;Fox JG;Backert S;Smet A;Boyen F;Haesebrouck F
通讯作者:
Haesebrouck F
影响因子:
9.4
作者:
Blosser, Sara J.;Drake, Steven K.;Zelazny, Adrian M.
通讯作者:
Zelazny, Adrian M.
影响因子:
14.2
作者:
Bader, O.;Weig, M.;Kuhns, M.
通讯作者:
Kuhns, M.
影响因子:
2.6
作者:
Curtoni, Antonio;Cipriani, Raffaella;Costa, Cristina
通讯作者:
Costa, Cristina