Microbiota inoculum composition affects holobiont assembly and host growth in Daphnia.
Microbiota inoculum composition affects holobiont assembly and host growth in Daphnia.
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DOI：
10.1186/s40168-018-0444-1
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发表时间：
2018-03-22
期刊：
影响因子：
15.5
通讯作者：
Decaestecker E
中科院分区：
文献类型：
--
作者：
Callens M;Watanabe H;Kato Y;Miura J;Decaestecker E
宿主相关的微生物群通常是通过环境中存在的微生物的水平传播获得的。据推测，定植菌环境池的差异会影响宿主上微生物群落的聚集，从而影响整体生物组成和宿主的适应性。为了验证这一假设，我们用不同浓度的抗生素土霉素干扰了无脊椎动物生态（毒性）逻辑模型水蚤的宿主相关微生物群。通过接种无菌个体，研究了受干扰微生物群定殖时水蚤群落的聚集和宿主-微生物群的相互作用。抗生素引起的微生物群紊乱通过影响微生物群成员之间的生态相互作用，对水蚤随后的定植产生强烈影响。这导致了群落聚集的差异，进而影响了水蚤的生长。这些结果表明，定殖菌群池的组成可能是水蚤上微生物群组合的重要结构因素，影响着菌群组成和寄主生长。这些发现有助于更好地理解微生物环境如何塑造全息生物组成并影响宿主-微生物群的相互作用。
Host-associated microbiota is often acquired by horizontal transmission of microbes present in the environment. It is hypothesized that differences in the environmental pool of colonizers can influence microbiota community assembly on the host and as such affect holobiont composition and host fitness. To investigate this hypothesis, the host-associated microbiota of the invertebrate eco(toxico)logical model Daphnia was experimentally disturbed using different concentrations of the antibiotic oxytetracycline. The community assembly and host-microbiota interactions when Daphnia were colonized by the disturbed microbiota were investigated by inoculating germ-free individuals with the microbiota. Antibiotic-induced disturbance of the microbiota had a strong effect on the subsequent colonization of Daphnia by affecting ecological interactions between members of the microbiota. This resulted in differences in community assembly which, in turn, affected Daphnia growth. These results show that the composition of the pool of colonizing microbiota can be an important structuring factor of the microbiota assembly on Daphnia, affecting holobiont composition and host growth. These findings contribute to a better understanding of how the microbial environment can shape the holobiont composition and affect host-microbiota interactions.
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DOI：
10.1126/science.1224203
发表时间：
2012-06-08
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Costello EK;Stagaman K;Dethlefsen L;Bohannan BJ;Relman DA
通讯作者：
Relman DA
影响因子：
9.8
作者：
Bordenstein SR;Theis KR
通讯作者：
Theis KR
影响因子：
48
作者：
Callahan BJ;McMurdie PJ;Rosen MJ;Han AW;Johnson AJ;Holmes SP
通讯作者：
Holmes SP
影响因子：
4.4
作者：
Kozich, James J.;Westcott, Sarah L.;Schloss, Patrick D.
通讯作者：
Schloss, Patrick D.
影响因子：
12.8
作者：
ELENDT, BP;BIAS, WR
通讯作者：
BIAS, WR