PRISM: a web server and repository for prediction of protein-protein interactions and modeling their 3D complexes.

PRISM: a web server and repository for prediction of protein-protein interactions and modeling their 3D complexes.
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DOI:
10.1093/nar/gku397
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发表时间:
2014-07
影响因子:
14.9
通讯作者:
Gursoy A
Gursoy A
中科院分区:
生物学2区
文献类型:
--
作者:
Baspinar A;Cukuroglu E;Nussinov R;Keskin O;Gursoy A

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PRISM网络服务器能够快速准确地预测蛋白质-蛋白质相互作用(PPI)。该预测算法是基于知识的。它结合了结构相似性,并考虑了模板界面的进化保守性。预测的模型存储在其存储库中。给定两种蛋白质结构,如果有匹配的模板界面,PRISM将提供其复合体的结构模型。用户可以下载复杂结构,检索界面残基,并可视化复杂模型。PRISM Web服务器是用户友好的,免费的,对http://cosbi.ku.edu.tr/prism.的所有用户开放
The PRISM web server enables fast and accurate prediction of protein–protein interactions (PPIs). The prediction algorithm is knowledge-based. It combines structural similarity and accounts for evolutionary conservation in the template interfaces. The predicted models are stored in its repository. Given two protein structures, PRISM will provide a structural model of their complex if a matching template interface is available. Users can download the complex structure, retrieve the interface residues and visualize the complex model. The PRISM web server is user friendly, free and open to all users at http://cosbi.ku.edu.tr/prism.
DOI: 10.1371/journal.pone.0086738
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者:
Cukuroglu E;Gursoy A;Nussinov R;Keskin O
通讯作者: Keskin O
DOI: 10.1038/nprot.2011.367
发表时间: 2011-08-11
期刊: Nature protocols
影响因子: 14.8
作者:
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通讯作者: Keskin O
蛋白质 - 蛋白质复合结构通过多聚螺纹和模板重组进行预测。
DOI: 10.1016/j.str.2011.04.006
发表时间: 2011-07-13
期刊: STRUCTURE
影响因子: 5.7
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DOI: 10.1002/prot.24022
发表时间: 2012-04
期刊: Proteins
影响因子: 2.9
作者:
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通讯作者: Gursoy A
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发表时间: 2009-01
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影响因子: 48
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