Metabolic effects of smoking cessation.

Metabolic effects of smoking cessation.
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DOI:
10.1038/nrendo.2016.32
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发表时间:
2016-05
期刊:
Nature reviews. Endocrinology
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其他
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在美国,吸烟仍然是导致可预防死亡的主要原因,尽管吸烟对健康的负面影响已经广为人知。数据显示,随着时间的推移,戒烟通常伴随着体重增加和胰岛素敏感性的改善。然而,矛盾的是,戒烟后相关的肥胖可能会导致胰岛素抵抗。此外,据报道,戒烟后体重增加是吸烟者(尤其是女性)戒烟失败或戒烟后复发的头号原因。在这篇综述中,我们讨论了戒烟对代谢的影响,并强调了戒烟计划和治疗设计的未来考虑,重点是减少戒烟后的体重增加。
Smoking continues to be the leading cause of preventable death in the USA, despite the vast and widely publicized knowledge about the negative health effects of tobacco smoking. Data show that smoking cessation is often accompanied by weight gain and an improvement in insulin sensitivity over time. However, paradoxically, post-cessation-related obesity might contribute to insulin resistance. Furthermore, post-cessation weight gain is reportedly the number one reason why smokers, especially women, fail to initiate smoking cessation or relapse after initiating smoking cessation. In this Review, we discuss the metabolic effects of stopping smoking and highlight future considerations for smoking cessation programs and therapies to be designed with an emphasis on reducing post-cessation weight gain.
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