Optimal boundary control of cardiac alternans

Optimal boundary control of cardiac alternans
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心脏交替的最佳边界控制

DOI:
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发表时间:
2007
期刊:
American Control Conference
影响因子:
--
通讯作者:
S. Dubljevic
S. Dubljevic
中科院分区:
--
文献类型:
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作者:
S. Dubljevic

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心肌正常电活动的交替被认为与危及生命的室性心律失常和心源性猝死的发生有关。本文用边界最优控制方法稳定了抛物型偏微分方程描述的空间均匀小振幅交替不稳定稳态。在全状态反馈控制结构中采用有限维线性二次型调节器(LQR),实现了有限尺寸组织缆长度的全局镇定。根据交替幅值方程的结构和所采用的控制方法,分析了该控制算法的实现能力。索引术语:心脏交替,动作电位传播,耗散抛物偏微分方程,LQR,最优边界控制。
Alternation of normal electrical activity in the myocardium is believed to be linked to the onset of life threatening ventricular arrhythmias and sudden cardiac death. In this paper, spatially uniform unstable steady state of small amplitude of alternans described by parabolic PDEs is stabilized by boundary optimal control method. Finite dimensional linear quadratic regulator (LQR) is utilized in the full state feedback control structure and it achieves global stabilization in the finite size tissue cable length. Ability to realize such control algorithm is analyzed based on the structure of the amplitude of alternans equation and control methodology applied. Index Terms: Cardiac Alternans, Action Potential Propagation, Dissipative Parabolic PDEs, LQR, Optimal Boundary Control.
DOI: 10.1161/01.cir.99.10.1385
发表时间: 1999-03-16
期刊: CIRCULATION
影响因子: 37.8
作者:
Pastore, JM;Girouard, SD;Rosenbaum, DS
通讯作者: Rosenbaum, DS
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DOI: 10.1103/physreve.71.051911
发表时间: 2005
期刊: Physical review. E, Statistical, nonlinear, and soft matter physics .
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发表时间: 2006-03-17
影响因子: 8.6
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