Waist-hip ratio and breast cancer risk in urbanized Nigerian women.

Waist-hip ratio and breast cancer risk in urbanized Nigerian women.
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城市化尼日利亚妇女的腰围比和乳腺癌风险。

DOI:
10.1186/bcr567
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发表时间:
2003
影响因子:
7.4
通讯作者:
Olopade, OI
Olopade, OI
中科院分区:
医学1区
文献类型:
--
作者:
Adebamowo, CA;Ogundiran, TO;Adenipekun, AA;Oyesegun, RA;Campbell, OB;Akang, EE;Rotimi, CN;Olopade, OI

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本研究的目的是探讨尼日利亚城市人口腰臀比与乳腺癌风险之间的关系。 1998 年 3 月至 2000 年 8 月期间,我们利用尼日利亚西南部城市的护士访谈员对医院乳腺癌患者 (n = 234) 和人群对照 (n = 273) 进行了病例对照研究。多变量逻辑回归显示绝经后女性腰臀比最高三分位数与乳腺癌风险之间存在显着相关性(比值比 = 2.67,95% 置信区间 = 1.05–6.80)。在绝经前女性中没有发现关联。本研究是第一项针对非洲土著人群的研究,支持了其他研究,这些研究表明绝经后妇女的肥胖与乳腺癌风险之间存在正相关关系。
The aim of this study was to examine the relationship between waist–hip ratio and the risk of breast cancer in an urban Nigerian population. Between March 1998 and August 2000, we conducted a case–control study of hospital-based breast cancer patients (n = 234) and population-based controls (n = 273) using nurse interviewers in urban Southwestern Nigeria. Multivariable logistic regression showed a significant association between the highest tertile of waist–hip ratio and the risk of breast cancer (odds ratio= 2.67, 95% confidence interval = 1.05–6.80) among postmenopausal women. No association was found in premenopausal women. The present study, the first in an indigenous African population, supports other studies that have shown a positive association between obesity and breast cancer risk among postmenopausal women.
DOI: 10.1038/sj.ijo.0800542
发表时间: 1998-01-01
影响因子: 4.9
作者:
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