SF-36 includes less Parkinson Disease (PD)-targeted content but is more responsive to change than two PD-targeted health-related quality of life measures.
SF-36 includes less Parkinson Disease (PD)-targeted content but is more responsive to change than two PD-targeted health-related quality of life measures.
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DOI：
10.1007/s11136-009-9530-y
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发表时间：
2009-11
影响因子：
3.5
通讯作者：
Vickrey, Barbara G.
中科院分区：
文献类型：
--
作者：
Brown, Carlos A.;Cheng, Eric M.;Hays, Ron D.;Vassar, Stefanie D.;Vickrey, Barbara G.
比较通用（SF-36）和帕金森病（PD）靶向（PDQ-39; PDQIF）健康相关生活质量（HRQOL）指标的有效性（包括反应性）、内部一致性可靠性和量表假设。在基线和18个月时，通过电话访谈对96例PD患者进行所有HRQOL测量。相对于四个外部标准（PD的日常影响，全球生活质量，PD症状的严重程度，抑郁症筛查自我评级）的相对效率和反应性进行了比较。我们通过对HRQOL量表/项目的标准变量进行回归，研究PD目标测量是否解释了SF-36之外的独特方差。通过项目与量表的相关性，探讨了PD目标测量的原始量表的准确性。在所有标准中，通用和PD靶向措施的相对效率估计值相似。反应性分析显示，SF-36对两个标准变量中的每一个的8个量表中的3个产生了较大（>0.8）的效应量（ES），而在PD目标测量中的任何量表中只有一个较大的ES。与仅使用SF-36量表的模型相比，在包含PD目标项目的回归模型中，调整后的R2从14%增加到27%。项目规模的相关性显示了显着的交叉负荷的项目跨规模的PD为目标的措施。SF-36的反应性优于两个PD目标指标，但这些指标的内容，显着解释PD患者的HRQOL。
To compare validity including responsiveness, and internal consistency reliability and scaling assumptions of a generic (SF-36) and Parkinson Disease (PD)-targeted (PDQ-39; PDQUALIF) health-related quality of life (HRQOL) measures. Ninety-six PD patients were administered for all HRQOL measures by telephonic interview at baseline and 18 months. Relative efficiency and responsiveness were compared relative to four external criteria (self-ratings of PD’s daily effects, global Quality of Life, PD symptom severity, and a depression screener). We examined whether PD-targeted measures explained unique variance beyond the SF-36 by regressing criterion variables on HRQOL scales/items. Adequacy of PD-targeted measures’ original scaling was explored by item-scale correlations. Relative efficiency estimates were similar for generic and PD-targeted measures across all criteria. Responsiveness analyses showed that the SF-36 yielded large (>0.8) effect sizes (ES) for three of eight scales for each of two criterion variables, compared to only one large ES for any scale in either PD-targeted measure. Adjusted R2 increased from 14 to 27% in regression models that included PD-targeted items compared to models with only SF-36 scales. Item-scale correlations showed significant cross-loading of items across scales of the PD-targeted measures. SF-36 responsiveness was better than that of two PD-targeted measures, yet those measures had content that significantly explains PD patients’ HRQOL.
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影响因子：
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作者：
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