Dietary Effects on Monocyte Phenotypes in Subjects With Hypertriglyceridemia and Metabolic Syndrome.
Dietary Effects on Monocyte Phenotypes in Subjects With Hypertriglyceridemia and Metabolic Syndrome.
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DOI:
10.1016/j.jacbts.2023.02.011
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发表时间:
2023-05
影响因子:
9.7
通讯作者:
Wu, Huaizhu
中科院分区:
文献类型:
--
作者:
Lian, Zeqin;Perrard, Xiao-Yuan Dai;Antony, Antu Kalathookunnel;Peng, Xueying;Xu, Lu;Ni, Jing;Zhang, Bingqian;'Brien, Veronica;Saeed, Anum;Jia, Xiaoming;Hussain, Aliza;Yu, Bing;Simon, Scott I.;Sacks, Frank M.;Hoogeveen, Ron C.;Ballantyne, Christie M.;Wu, Huaizhu
Hypertriglyceridemia and metabolic syndrome increase the risk for atherosclerotic cardiovascular disease. Dietary composition may affect plasma levels of triglycerides and therefore the risk for atherosclerotic cardiovascular disease. In patients with hypertriglyceridemia and metabolic syndrome, a short-term randomized LSFD vs HSFD induced lower plasma levels of postprandial triglyceride and LDL-triglyceride and fasting and postprandial total cholesterol and LDL cholesterol, decreased monocyte intracellular lipid accumulation, and reduced monocyte adhesion and oxidized LDL uptake. These findings highlight the importance of dietary fat content and composition for monocyte phenotypes and possibly atherosclerotic cardiovascular disease risk in patients with hypertriglyceridemia and metabolic syndrome. In patients with hypertriglyceridemia, a short-term low–saturated fat vs high–saturated fat diet induced lower plasma lipids and improved monocyte phenotypes. These findings highlight the role of diet fat content and composition for monocyte phenotypes and possibly cardiovascular disease risk in these patients. (Effects of Dietary Interventions on Monocytes in Metabolic Syndrome; NCT03591588)
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影响因子:
30.5
作者:
Koelwyn GJ;Corr EM;Erbay E;Moore KJ
通讯作者:
Moore KJ
DOI:
10.1161/atvbaha.120.315886
发表时间:
2021-05-05
期刊:
Arteriosclerosis, thrombosis, and vascular biology
影响因子:
--
作者:
Feinstein MJ;Doyle MF;Stein JH;Sitlani CM;Fohner AE;Huber SA;Landay AL;Heckbert SR;Rice K;Kronmal RA;Hedrick C;Manichaikul A;McNamara C;Rich S;Tracy RP;Olson NC;Psaty BM;Delaney JAC
通讯作者:
Delaney JAC
DOI:
10.1161/atvbaha.113.302077
发表时间:
2014-01
期刊:
Arteriosclerosis, thrombosis, and vascular biology
影响因子:
--
作者:
Jiang E;Perrard XD;Yang D;Khan IM;Perrard JL;Smith CW;Ballantyne CM;Wu H
通讯作者:
Wu H
影响因子:
5.8
作者:
Khan, Ilvira M.;Pokharel, Yashashwi;Ballantyne, Christie M.
通讯作者:
Ballantyne, Christie M.
影响因子:
20.1
作者:
Depuydt MAC;Prange KHM;Slenders L;Örd T;Elbersen D;Boltjes A;de Jager SCA;Asselbergs FW;de Borst GJ;Aavik E;Lönnberg T;Lutgens E;Glass CK;den Ruijter HM;Kaikkonen MU;Bot I;Slütter B;van der Laan SW;Yla-Herttuala S;Mokry M;Kuiper J;de Winther MPJ;Pasterkamp G
通讯作者:
Pasterkamp G