Uthando Lwethu ('our love'): a protocol for a couples-based intervention to increase testing for HIV: a randomized controlled trial in rural KwaZulu-Natal, South Africa.
Uthando Lwethu ('our love'): a protocol for a couples-based intervention to increase testing for HIV: a randomized controlled trial in rural KwaZulu-Natal, South Africa.
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DOI：
10.1186/1745-6215-15-64
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发表时间：
2014-02-20
期刊：
影响因子：
2.5
通讯作者：
McGrath N
中科院分区：
文献类型：
--
作者：
Darbes LA;van Rooyen H;Hosegood V;Ngubane T;Johnson MO;Fritz K;McGrath N
以夫妻为基础的艾滋病毒咨询和检测(CHCT)是一种行之有效的策略，可以降低艾滋病毒在伴侣之间传播的风险，但CHCT的接受率很低。我们描述了一项随机对照试验(RCT)的研究设计，该试验旨在增加在南非夸祖鲁-纳塔尔农村地区异性伴侣中参与CHCT并减少HIV的性危险行为。我们假设，与对照组相比，干预组的CHCT参与率更高，性危险行为更低。异性伴侣(N = 350对夫妇，700人)正在被招募参加一项以夫妇为基础的干预的随机试验，该试验包括两个小组会议(一个混合性别，一个单一性别)和四个夫妇咨询会议。情侣们必须在一起至少6个月。量化评估由性别匹配的面试者在随机化后的基线、3、6和9个月通过手机进行。干预内容旨在改善关系动态，包括沟通技能和制定关于CHCT的目标。Uthan do Lwethu(我们的爱)干预是第一个以CHCT为结果的以夫妻为基础的干预。我们的目标也是减少无保护措施的性行为。CHCT需要双方进行检测和相互披露，这些条件对于改善后续结果至关重要，如披露艾滋病毒状况、减少性风险和改善治疗结果。因此，在受艾滋病毒严重影响的南非农村地区，提高CHCT率有可能改善异性伴侣的健康结果。我们正在进行的临床试验的结果将提供急需的信息，关于注重关系的方法是否在提高CHCT的参与率方面有效。我们的干预表明，我们试图摆脱个人层面的概念化，转向更综合的艾滋病毒预防方法。研究名称：上下文中的夫妇：一项基于夫妇的艾滋病毒预防干预诊所的RCT试验.gov标识：NCT01953133。南非临床试验注册号：DOH-27-0212-3937
Couples-based HIV counseling and testing (CHCT) is a proven strategy to reduce the risk of HIV transmission between partners, but uptake of CHCT is low. We describe the study design of a randomized controlled trial (RCT) aimed to increase participation in CHCT and reduce sexual risk behavior for HIV among heterosexual couples in rural KwaZulu-Natal, South Africa. We hypothesize that the rate of participation in CHCT will be higher and sexual risk behavior will be lower in the intervention group as compared to the control. Heterosexual couples (N = 350 couples, 700 individuals) are being recruited to participate in a randomized trial of a couples-based intervention comprising two group sessions (one mixed gender, one single gender) and four couples’ counseling sessions. Couples must have been in a relationship together for at least 6 months. Quantitative assessments are conducted via mobile phones by gender-matched interviewers at baseline, 3, 6, and 9 months post-randomization. Intervention content is aimed to improve relationship dynamics, and includes communication skills and setting goals regarding CHCT. The Uthando Lwethu (‘our love’) intervention is the first couples-based intervention to have CHCT as its outcome. We are also targeting reductions in unprotected sex. CHCT necessitates the testing and mutual disclosure of both partners, conditions that are essential for improving subsequent outcomes such as disclosure of HIV status, sexual risk reduction, and improving treatment outcomes. Thus, improving rates of CHCT has the potential to improve health outcomes for heterosexual couples in a rural area of South Africa that is highly impacted by HIV. The results of our ongoing clinical trial will provide much needed information regarding whether a relationship-focused approach is effective in increasing rates of participation in CHCT. Our intervention represents an attempt to move away from individual-level conceptualizations, to a more integrated approach for HIV prevention. Study Name: Couples in Context: An RCT of a Couples-based HIV Prevention Intervention ClinicalTrials.gov identifier: NCT01953133. South African clinical trial registration number: DOH-27-0212-3937
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影响因子：
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