Daily temporal dynamics of vaginal microbiota before, during and after episodes of bacterial vaginosis.
Daily temporal dynamics of vaginal microbiota before, during and after episodes of bacterial vaginosis.
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DOI:
10.1186/2049-2618-1-29
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发表时间:
2013-12-02
期刊:
影响因子:
15.5
通讯作者:
Forney LJ
中科院分区:
文献类型:
--
作者:
Ravel J;Brotman RM;Gajer P;Ma B;Nandy M;Fadrosh DW;Sakamoto J;Koenig SS;Fu L;Zhou X;Hickey RJ;Schwebke JR;Forney LJ
Bacterial vaginosis (BV) is a common gynecologic diagnosis characterized by dysbiosis of the vaginal microbiota. It is often accompanied by vaginal symptoms such as odor and discharge, but can be asymptomatic. Despite over 50 years of research, the etiology of BV is not well understood, which is a major impediment to treatment and prevention of BV. Here we report on the temporal dynamics of 25 vaginal communities over a 10 week period using samples collected daily from women who were diagnosed with symptomatic BV (15 women), asymptomatic BV (6 women), and women who did not have BV (4 women). This unique resource of samples and data will contribute to a better understanding of the role that the vaginal microbes have in the natural history of BV and lead to improved diagnosis and treatment.
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影响因子:
3.7
作者:
Srinivasan S;Hoffman NG;Morgan MT;Matsen FA;Fiedler TL;Hall RW;Ross FJ;McCoy CO;Bumgarner R;Marrazzo JM;Fredricks DN
通讯作者:
Fredricks DN
DOI:
10.1038/ismej.2012.8
发表时间:
2012-08
期刊:
The ISME journal
影响因子:
--
作者:
通讯作者:
--
影响因子:
9.4
作者:
Forney, Larry J.;Gajer, Pawel;Ravel, Jacques
通讯作者:
Ravel, Jacques
影响因子:
3.7
作者:
Srinivasan S;Liu C;Mitchell CM;Fiedler TL;Thomas KK;Agnew KJ;Marrazzo JM;Fredricks DN
通讯作者:
Fredricks DN
影响因子:
3.6
作者:
Ison, CA;Hay, PE
通讯作者:
Hay, PE