Ultrastructural examination of diffuse and specific tectopulvinar projections in the tree shrew.
Ultrastructural examination of diffuse and specific tectopulvinar projections in the tree shrew.
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DOI：
10.1002/cne.21763
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发表时间：
2008-09-01
影响因子：
2.5
通讯作者：
Bickford, Martha E.
中科院分区：
文献类型：
--
作者：
Chomsung, Ranida D.;Petry, Heywood M.;Bickford, Martha E.
关键词：
已经描述了从上丘(SC)到树鼠枕核的两条路径，一条是轴突以密集的(或特定的)斑块终止，另一条是轴突茎更分散地组织(Luppino等人)。[1988]J.Comp.神经。273：67-86)。正如里昂等人预测的那样。[2003]J.Comp.神经。467：593-606)，我们发现弥漫顶盖尺神经通路的顺行标记终止于富含乙酰胆碱酯酶(AChE)的背枕(Pd)，而特定通路终止于AChE缺乏的中央枕(Pc)。逆行注射PD标记的非γ-氨基丁酸能广域垂直细胞位于内侧SC的灰质浅层下层和视层，而Pc标记的类似细胞位于更外侧的区域。在超微结构水平上，我们发现PD和Pc的顶盖-尺神经终末主要接触非GABA能树突。然而，当存在时，GABA能谱上的突触接触在Pc(占所有接触的31%)比Pd(16%)更常见。与PD(4%)相比，Pc(19%)与Pd(4%)相比，被标记为2型囊泡谷氨酸转运体的终末在Pc(19%)中也接触到更多的GABA能谱。这些结果为树鼠枕被划分为两个不同的构造接受区提供了强有力的证据。讨论了这些途径的潜在功能。J.Comp.神经。510：24-46,2008。
Two pathways from the superior colliculus (SC) to the tree shrew pulvinar nucleus have been described, one in which the axons terminate in dense (or specific) patches and one in which the axon arbors are more diffusely organized (Luppino et al. [1988] J. Comp. Neurol. 273:67– 86). As predicted by Lyon et al. ([2003] J. Comp. Neurol. 467:593– 606), we found that anterograde labeling of the diffuse tectopulvinar pathway terminated in the acetylcholinesterase (AChE)-rich dorsal pulvinar (Pd), whereas the specific pathway terminated in the AChE-poor central pulvinar (Pc). Injections of retrograde tracers in Pd labeled non-γ-aminobutyric acid (GABA)-ergic wide-field vertical cells located in the lower stratum griseum superficiale and stratum opticum of the medial SC, whereas injections in Pc labeled similar cells in more lateral regions. At the ultrastructural level, we found that tectopulvinar terminals in both Pd and Pc contact primarily non-GABAergic dendrites. When present, however, synaptic contacts on GABAergic profiles were observed more frequently in Pc (31% of all contacts) compared with Pd (16%). Terminals stained for the type 2 vesicular glutamate transporter, a potential marker of tectopulvinar terminals, also contacted more GABAergic profiles in Pc (19%) compared with Pd (4%). These results provide strong evidence for the division of the tree shrew pulvinar into two distinct tectorecipient zones. The potential functions of these pathways are discussed. J. Comp. Neurol. 510:24 – 46, 2008.
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影响因子：
2.5
作者：
ABRAMSON, BP;CHALUPA, LM
通讯作者：
CHALUPA, LM
影响因子：
2.5
作者：
FITZPATRICK, D;CONLEY, M;DIAMOND, IT
通讯作者：
DIAMOND, IT
DOI：
10.1007/bf00325634
发表时间：
1971-01-01
期刊：
ZEITSCHRIFT FUR ZELLFORSCHUNG UND MIKROSKOPISCHE ANATOMIE
影响因子：
--
作者：
GENESERJENSEN, FA;BLACKSTAD, TW
通讯作者：
BLACKSTAD, TW
影响因子：
2.9
作者：
Jiang, ZD;King, AJ;Moore, DR
通讯作者：
Moore, DR
影响因子：
2.5
作者：
Dankowski, A;Bickford, ME
通讯作者：
Bickford, ME