RNAcentral: a hub of information for non-coding RNA sequences.

RNAcentral: a hub of information for non-coding RNA sequences.
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DOI:
10.1093/nar/gky1034
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发表时间:
2019-01-08
影响因子:
14.9
通讯作者:
The RNAcentral Consortium
The RNAcentral Consortium
中科院分区:
生物学2区
文献类型:
--
作者:
The RNAcentral Consortium

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rnacentral是一个非编码RNA(NCRNA)序列的综合数据库,对来自广泛生物的所有类型的NCRNA序列进行了整理。我们最近添加了一个新的基因组映射管道,该管道可以确定296种NCRNA序列的基因组位置。我们还添加了几种新型的功能注释,例如tRNA二级结构,基因本体学注释和miRNA-target相互作用。基于RFAM家族分配的新质量控制机制可确定潜在的污染,不完整的序列等。 rnacentral数据库已成为RNA社区许多工作流的重要组成部分,既是学术和商业组的序列数据的主要来源,也是稳定的基因组和功能功能注释的稳定加入来源。这些示例由改进的rnacentral Web界面促进,该界面具有更新的基因组浏览器,新的序列功能查看器以及改进的文本搜索功能。 rnacentral可在https://rnacentral.org上免费获得。
RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences, collating information on ncRNA sequences of all types from a broad range of organisms. We have recently added a new genome mapping pipeline that identifies genomic locations for ncRNA sequences in 296 species. We have also added several new types of functional annotations, such as tRNA secondary structures, Gene Ontology annotations, and miRNA-target interactions. A new quality control mechanism based on Rfam family assignments identifies potential contamination, incomplete sequences, and more. The RNAcentral database has become a vital component of many workflows in the RNA community, serving as both the primary source of sequence data for academic and commercial groups, as well as a source of stable accessions for the annotation of genomic and functional features. These examples are facilitated by an improved RNAcentral web interface, which features an updated genome browser, a new sequence feature viewer, and improved text search functionality. RNAcentral is freely available at https://rnacentral.org.
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