Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project.
Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project.
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DOI：
10.1016/j.earlhumdev.2018.04.004
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发表时间：
2018-05
影响因子：
2.5
通讯作者：
Silventoinen K
中科院分区：
文献类型：
--
作者：
Jelenkovic A;Yokoyama Y;Sund R;Hur YM;Harris JR;Brandt I;Nilsen TS;Ooki S;Ullemar V;Almqvist C;Magnusson PKE;Saudino KJ;Stazi MA;Fagnani C;Brescianini S;Nelson TL;Whitfield KE;Knafo-Noam A;Mankuta D;Abramson L;Cutler TL;Hopper JL;Llewellyn CH;Fisher A;Corley RP;Huibregtse BM;Derom CA;Vlietinck RF;Bjerregaard-Andersen M;Beck-Nielsen H;Sodemann M;Krueger RF;McGue M;Pahlen S;Alexandra Burt S;Klump KL;Dubois L;Boivin M;Brendgen M;Dionne G;Vitaro F;Willemsen G;Bartels M;van Beijsterveld CEM;Craig JM;Saffery R;Rasmussen F;Tynelius P;Heikkilä K;Pietiläinen KH;Bayasgalan G;Narandalai D;Haworth CMA;Plomin R;Ji F;Ning F;Pang Z;Rebato E;Tarnoki AD;Tarnoki DL;Kim J;Lee J;Lee S;Sung J;Loos RJF;Boomsma DI;Sørensen TIA;Kaprio J;Silventoinen K
有证据表明，出生时的体型与日后的身高呈正相关，但目前尚不清楚这是由遗传因素还是宫内环境造成的。分析单卵双胞胎和双卵双胞胎从婴儿期到成年期的出生体重、身长和体重指数与身高的关系，从而深入了解遗传和环境个体特异性因素的作用。这项研究是基于来自17个国家的28个双胞胎队列的数据。汇总数据包括41，852对完整双胞胎（55%为同卵双胞胎，45%为同性异卵双胞胎），其中包含出生体重信息，以及总计112，409对年龄从1岁到69岁不等的身高测量结果。19，881对完整双胞胎的出生长度可用，共有72，692对身高测量。通过线性回归分析，在个体和配对水平上分析了出生大小和后期身高之间的关联。在双胞胎中，回归系数显示，出生体重增加1公斤和出生身长增加1厘米分别与身高增加1.14-4.25厘米和0.18-0.90厘米有关。这种关联的程度一般在双卵双胞胎中比在单卵双胞胎中更大，并且这种合子之间的差异在出生长度上更明显。遗传和个体特异性环境因素在出生大小与婴儿期到成年期的身高之间的关联中发挥作用，遗传学在与出生长度的关联中的作用大于与出生体重的关联。
There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. To analyze the associations of birth weight, length and ponderal index with height from infancy through adulthood within mono- and dizygotic twin pairs, which provides insights into the role of genetic and environmental individual-specific factors. This study is based on the data from 28 twin cohorts in 17 countries. The pooled data included 41,852 complete twin pairs (55% monozygotic and 45% same-sex dizygotic) with information on birth weight and a total of 112,409 paired height measurements at ages ranging from 1 to 69 years. Birth length was available for 19,881 complete twin pairs, with a total of 72,692 paired height measurements. The association between birth size and later height was analyzed at both the individual and within-pair level by linear regression analyses. Within twin pairs, regression coefficients showed that a 1-kg increase in birth weight and a 1-cm increase in birth length were associated with 1.14–4.25 cm and 0.18–0.90 cm taller height, respectively. The magnitude of the associations was generally greater within dizygotic than within monozygotic twin pairs, and this difference between zygosities was more pronounced for birth length. Both genetic and individual-specific environmental factors play a role in the association between birth size and later height from infancy to adulthood, with a larger role for genetics in the association with birth length than with birth weight.
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影响因子：
64.8
作者：
Horikoshi, Momoko;Beaumont, Robin N.;Day, Felix R.;Warrington, Nicole M.;Kooijman, Marjolein N.;Fernandez-Tajes, Juan;Feenstra, Bjarke;van Zuydam, Natalie R.;Gaulton, Kyle J.;Grarup, Niels;Bradfield, Jonathan P.;Strachan, David P.;Li-Gao, Ruifang;Ahluwalia, Tarunveer S.;Kreiner, Eskil;Rueedi, Rico;Lyytikainen, Leo-Pekka;Cousminer, Diana L.;Wu, Ying;Thiering, Elisabeth;Wang, Carol A.;Have, Christian T.;Hottenga, Jouke-Jan;Vilor-Tejedor, Natalia;Joshi, Peter K.;Boh, Eileen Tai Hui;Ntalla, Ioanna;Pitkanen, Niina;Mahajan, Anubha;van Leeuwen, Elisabeth M.;Joro, Raimo;Lagou, Vasiliki;Nodzenski, Michael;Diver, Louise A.;Zondervan, Krina T.;Bustamante, Mariona;Marques-Vidal, Pedro;Mercader, Josep M.;Bennett, Amanda J.;Rahmioglu, Nilufer;Nyholt, Dale R.;Ma, Ronald C. W.;Tam, Claudia H. T.;Tam, Wing Hung;Ganesh, Santhi K.;van Rooij, Frank J. A.;Jones, Samuel E.;Loh, Po-Ru;Ruth, Katherine S.;Tuke, Marcus A.;Tyrrell, Jessica;Wood, Andrew R.;Yaghootkar, Hanieh;Scholtens, Denise M.;Paternoster, Lavinia;Prokopenko, Inga;Kovacs, Peter;Atalay, Mustafa;Willems, Sara M.;Panoutsopoulou, Kalliope;Wang, Xu;Carstensen, Lisbeth;Geller, Frank;Schraut, Katharina E.;Murcia, Mario;van Beijsterveldt, Catharina E. M.;Willemsen, Gonneke;Appel, Emil V. R.;Fonvig, Cilius E.;Trier, Caecilie;Tiesler, Carla M. T.;Standl, Marie;Kutalik, Zoltan;Bonas-Guarch, Silvia;Hougaard, David M.;Sanchez, Friman;Torrents, David;Waage, Johannes;Hollegaard, Mads V.;de Haan, Hugoline G.;Rosendaal, Frits R.;Medina-Gomez, Carolina;Ring, Susan M.;Hemani, Gibran;McMahon, George;Robertson, Neil R.;Groves, Christopher J.;Langenberg, Claudia;Luan, Jian'an;Scott, Robert A.;Zhao, Jing Hua;Mentch, Frank D.;MacKenzie, Scott M.;Reynolds, Rebecca M.;Lowe, William L.;Toenjes, Anke;Stumvoll, Michael;Lindi, Virpi;Lakka, Timo A.;van Duijn, Cornelia M.;Kiess, Wieland;Koerner, Antje;Sorensen, Thorkild I. A.;Niinikoski, Harri;Pahkala, Katja;Raitakari, Olli T.;Zeggini, Eleftheria;Dedoussis, George V.;Teo, Yik-Ying;Saw, Seang-Mei;Melbye, Mads;Campbell, Harry;Wilson, James F.;Vrijheid, Martine;de Geus, Eco J. C. N.;Boomsma, Dorret I.;Kadarmideen, Haja N.;Holm, Jens-Christian;Hansen, Torben;Sebert, Sylvain;Hattersley, Andrew T.;Beilin, Lawrence J.;Newnham, John P.;Pennell, Craig E.;Heinrich, Joachim;Adair, Linda S.;Borja, Judith B.;Mohlke, Karen L.;Eriksson, Johan G.;Widen, Elisabeth;Kahonen, Mika;Viikari, Jorma S.;Lehtimaki, Terho;Vollenweider, Peter;Bonnelykke, Klaus;Bisgaard, Hans;Mook-Kanamori, Dennis O.;Hofman, Albert;Rivadeneira, Fernando;Uitterlinden, Andre G.;Pisinger, Charlotta;Pedersen, Oluf;Power, Christine;Hyppoenen, Elina;Wareham, Nicholas J.;Hakonarson, Hakon;Davies, Eleanor;Walker, Brian R.;Jaddoe, Vincent W. V.;Jaervelin, Marjo-Riitta;Grant, Struan F. A.;Vaag, Allan A.;Lawlor, Debbie A.;Frayling, Timothy M.;Smith, George Davey;Morris, Andrew P.;Ong, Ken K.;Felix, Janine F.;Timpson, Nicholas J.;Perry, John R. B.;Evans, David M.;McCarthy, Mark I.;Freathy, Rachel M.
通讯作者：
Freathy, Rachel M.
影响因子：
7.7
作者：
Jelenkovic A;Yokoyama Y;Sund R;Pietiläinen KH;Hur YM;Willemsen G;Bartels M;van Beijsterveldt TCEM;Ooki S;Saudino KJ;Stazi MA;Fagnani C;D'Ippolito C;Nelson TL;Whitfield KE;Knafo-Noam A;Mankuta D;Abramson L;Heikkilä K;Cutler TL;Hopper JL;Wardle J;Llewellyn CH;Fisher A;Corley RP;Huibregtse BM;Derom CA;Vlietinck RF;Loos RJF;Bjerregaard-Andersen M;Beck-Nielsen H;Sodemann M;Tarnoki AD;Tarnoki DL;Burt SA;Klump KL;Ordoñana JR;Sánchez-Romera JF;Colodro-Conde L;Dubois L;Boivin M;Brendgen M;Dionne G;Vitaro F;Harris JR;Brandt I;Nilsen TS;Craig JM;Saffery R;Rasmussen F;Tynelius P;Bayasgalan G;Narandalai D;Haworth CMA;Plomin R;Ji F;Ning F;Pang Z;Rebato E;Krueger RF;McGue M;Pahlen S;Boomsma DI;Sørensen TIA;Kaprio J;Silventoinen K
通讯作者：
Silventoinen K
影响因子：
7.1
作者：
ROWLAND, ML
通讯作者：
ROWLAND, ML
影响因子：
4.4
作者：
Bacallao, J;Amador, M;Hermelo, M
通讯作者：
Hermelo, M
影响因子：
168.9
作者：
KUSIN, JA;KARDJATI, S;RENQVIST, UH
通讯作者：
RENQVIST, UH