Identification of intra-individual variation in intracranial arterial flow by MRI and the effect on computed hemodynamic descriptors.
Identification of intra-individual variation in intracranial arterial flow by MRI and the effect on computed hemodynamic descriptors.
复制标题
DOI：
10.1007/s10334-021-00917-0
复制
发表时间：
2021-10
期刊：
影响因子：
--
通讯作者：
Saloner D
中科院分区：
文献类型：
--
作者：
Liu X;Kao E;Haraldsson H;Ballweber M;Martin A;Li Y;Wang Y;Saloner D
确定连续采集研究中的个体内流量变化，以及该变化对后续血流动力学模拟的影响（使用入口流量作为边界条件）。该前瞻性研究包括51例（37例女性和14例男性）接受3次以上2D相位对比MR随访的未破裂颅内动脉瘤患者。提取血流和速度参数以计算再现性和变异性。使用测量的流量进行患者特定的计算流体动力学模拟。组内相关系数的平均和最大速度和流量参数范围从0.77到0.90。确定了平均流量的10% CV。血流动力学变化包括收缩期峰值壁面切应力的41.41%、舒张末期壁面切应力的39.13%、收缩期峰值低切面积的2.79%、舒张末期低切面积的2.12%、时均壁面切应力的47.57%和振荡剪切指数的0.17%。本研究确定了10%的个体内平均流量变化的相位对比MR。个体内流量变化导致壁面剪切应力的不可忽略的变化，但在血流动力学计算中低剪切面积的变化相对较小。
To determine the intra-individual flow variation in serially acquired studies, and the influence of this variation on subsequent hemodynamic simulations using the inlet flow as a boundary condition. This prospective study included 51 patients (37 females and 14 males) with unruptured intracranial aneurysms who have received more than 3 times follow-up of 2D phase-contrast MR. The flow and velocity parameters were extracted to calculate the reproducibility and variation. Patient-specific computational fluid dynamics simulations were performed using the measured flows. Intraclass correlation coefficients for mean and maximum velocity and flow parameters ranged from 0.77 to 0.90. A 10% CV of mean flow was identified. Variations of 10% in inlet flow resulted in hemodynamic changes including 41.41% of peak systolic wall shear stress; 39.13% of end diastolic wall shear stress; 2.79% of low shear area at peak systole; 2.12% of low shear area at end diastole: 47.57% of time-averaged wall shear stress; and 0.17% of oscillatory shear index. This study identified 10% of intra-individual mean flow variation on phase-contrast MR. Intra individual flow variation resulted in a non-negligible variation in wall shear stress, but relatively small variation in low shear area in hemodynamic calculations.
登录
查看更多内容
影响因子：
37.8
作者：
Go AS;Mozaffarian D;Roger VL;Benjamin EJ;Berry JD;Blaha MJ;Dai S;Ford ES;Fox CS;Franco S;Fullerton HJ;Gillespie C;Hailpern SM;Heit JA;Howard VJ;Huffman MD;Judd SE;Kissela BM;Kittner SJ;Lackland DT;Lichtman JH;Lisabeth LD;Mackey RH;Magid DJ;Marcus GM;Marelli A;Matchar DB;McGuire DK;Mohler ER 3rd;Moy CS;Mussolino ME;Neumar RW;Nichol G;Pandey DK;Paynter NP;Reeves MJ;Sorlie PD;Stein J;Towfighi A;Turan TN;Virani SS;Wong ND;Woo D;Turner MB;American Heart Association Statistics Committee and Stroke Statistics Subcommittee
通讯作者：
American Heart Association Statistics Committee and Stroke Statistics Subcommittee
影响因子：
3.8
作者：
Leach, Joseph R.;Rayz, Vitaliy L.;Soares, Bruno;Wintermark, Max;Mofrad, Mohammad R. K.;Saloner, David
通讯作者：
Saloner, David
DOI：
10.3174/ajnr.a4358
发表时间：
2015-09
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
Cebral JR;Duan X;Chung BJ;Putman C;Aziz K;Robertson AM
通讯作者：
Robertson AM
影响因子：
3.3
作者：
Stalder, A. F.;Russe, M. F.;Markl, M.
通讯作者：
Markl, M.
影响因子：
2.8
作者：
de Verdier, Maria Correia;Wikstrom, Johan
通讯作者：
Wikstrom, Johan