How to assemble a beneficial microbiome in three easy steps.

How to assemble a beneficial microbiome in three easy steps.
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如何通过三个简单的步骤组装有益的微生物组

DOI:
10.1111/j.1461-0248.2012.01853.x
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发表时间:
2012-11
期刊:
影响因子:
8.8
通讯作者:
Yu DW
Yu DW
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Scheuring I;Yu DW

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人们对解释有益的微生物组是如何组装的很感兴趣。产生抗生素的微生物组可以说是自然界中最丰富的一类有益微生物组,已在珊瑚,节肢动物,软体动物,脊椎动物和植物根际中发现。一个例子是阿廷蚂蚁,它们培养一种真菌作为食物,并拥有一个表皮微生物组,释放抗生素来保护真菌免受寄生虫的侵害。一种解释是,这种细菌(以某种方式)在对抗寄生虫的军备竞赛中进化出新的化合物。或者,attines(不知何故)选择性地从土壤中招募多个非共同进化的放线菌属,从而实现针对寄生虫的“多药”策略。我们调和的模型表明,当主机燃料干扰竞争提供丰富的资源,干扰竞争有利于招聘的抗生素生产(和耐药)的细菌。当至少有一种放线菌共生体垂直传播或具有高迁移率时,这种伙伴选择机制更有效,如在疾病抑制土壤中。
There is great interest in explaining how beneficial microbiomes are assembled. Antibiotic-producing microbiomes are arguably the most abundant class of beneficial microbiome in nature, having been found on corals, arthropods, molluscs, vertebrates and plant rhizospheres. An exemplar is the attine ants, which cultivate a fungus for food and host a cuticular microbiome that releases antibiotics to defend the fungus from parasites. One explanation posits long-term vertical transmission of P seudonocardia bacteria, which (somehow) evolve new compounds in arms-race fashion against parasites. Alternatively, attines (somehow) selectively recruit multiple, non-coevolved actinobacterial genera from the soil, enabling a ‘multi-drug’ strategy against parasites. We reconcile the models by showing that when hosts fuel interference competition by providing abundant resources, the interference competition favours the recruitment of antibiotic-producing (and -resistant) bacteria. This partner-choice mechanism is more effective when at least one actinobacterial symbiont is vertically transmitted or has a high immigration rate, as in disease-suppressive soils.
DOI: 10.1126/science.1198719
发表时间: 2011-05-20
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Muegge BD;Kuczynski J;Knights D;Clemente JC;González A;Fontana L;Henrissat B;Knight R;Gordon JI
通讯作者: Gordon JI
DOI: 10.1086/657622
发表时间: 2011-01-01
影响因子: 2.9
作者:
Archetti, Marco;Ubeda, Francisco;Yu, Douglas W.
通讯作者: Yu, Douglas W.
DOI: 10.1038/19519
发表时间: 1999-04-22
期刊: NATURE
影响因子: 64.8
作者:
Currie, CR;Scott, JA;Malloch, D
通讯作者: Malloch, D
DOI: 10.1073/pnas.1934677100
发表时间: 2003-11-25
影响因子: 11.1
作者:
Challis, GL;Hopwood, DA
通讯作者: Hopwood, DA
DOI: 10.1111/j.1574-6976.2009.00193.x
发表时间: 2010-01
影响因子: 11.3
作者:
Chaston J;Goodrich-Blair H
通讯作者: Goodrich-Blair H