Visual experience induces 4-8 Hz synchrony between V1 and higher-order visual areas.
Visual experience induces 4-8 Hz synchrony between V1 and higher-order visual areas.
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DOI:
10.1016/j.celrep.2023.113482
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发表时间:
2023-12-26
期刊:
影响因子:
8.8
通讯作者:
中科院分区:
文献类型:
--
作者:
Visual perceptual experience induces persistent 4–8 Hz oscillations in the mouse primary visual cortex (V1), encoding visual familiarity. Recent studies suggest that higher-order visual areas (HVAs) are functionally specialized and segregated into information streams processing distinct visual features. However, whether visual memories are processed and stored within the distinct streams is not understood. We report here that V1 and lateromedial (LM), but not V1 and anterolateral, become more phase synchronized in 4–8 Hz after the entrainment of visual stimulus that maximally induces responses in LM. Directed information analysis reveals changes in the top-down functional connectivity between V1 and HVAs. Optogenetic inactivation of LM reduces post-stimulus oscillation peaks in V1 and impairs visual discrimination behavior. Our results demonstrate that 4–8 Hz familiarity-evoked oscillations are specific for the distinct visual features and are present in the corresponding HVAs, where they may be used for the inter-areal communication with V1 during memory-related behaviors. We demonstrate that visual familiarity induces 4–8 Hz synchrony between higher-order visual areas (HVAs) and V1 in mice. Directed information analysis revealed changes in the functional connectivity from HVAs to V1. Optogenetic inactivation of LM during the delay period after the visual stimulus reduced the 4–8 Hz oscillation amplitude in V1 and impaired visual discrimination behavior.
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影响因子:
16.2
作者:
Fries P
通讯作者:
Fries P
影响因子:
25
作者:
Glickfeld, Lindsey L.;Andermann, Mark L.;Bonin, Vincent;Reid, R. Clay
通讯作者:
Reid, R. Clay
DOI:
10.1523/jneurosci.1337-20.2021
发表时间:
2021-03-24
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Gao M;Lim S;Chubykin AA
通讯作者:
Chubykin AA
影响因子:
4.3
作者:
Gramfort A;Luessi M;Larson E;Engemann DA;Strohmeier D;Brodbeck C;Goj R;Jas M;Brooks T;Parkkonen L;Hämäläinen M
通讯作者:
Hämäläinen M
影响因子:
64.8
作者:
Harris JA;Mihalas S;Hirokawa KE;Whitesell JD;Choi H;Bernard A;Bohn P;Caldejon S;Casal L;Cho A;Feiner A;Feng D;Gaudreault N;Gerfen CR;Graddis N;Groblewski PA;Henry AM;Ho A;Howard R;Knox JE;Kuan L;Kuang X;Lecoq J;Lesnar P;Li Y;Luviano J;McConoughey S;Mortrud MT;Naeemi M;Ng L;Oh SW;Ouellette B;Shen E;Sorensen SA;Wakeman W;Wang Q;Wang Y;Williford A;Phillips JW;Jones AR;Koch C;Zeng H
通讯作者:
Zeng H