Therapeutic polymers for dental adhesives: loading resins with bio-active components.
Therapeutic polymers for dental adhesives: loading resins with bio-active components.
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DOI：
10.1016/j.dental.2013.06.003
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发表时间：
2014-01
期刊：
影响因子：
5
通讯作者：
Xu, Hockin H. K.
中科院分区：
文献类型：
--
作者：
Imazato, Satoshi;Ma, Sai;Chen, Ji-hua;Xu, Hockin H. K.
市场上许多新近上市的粘合剂都表现出了合理的临床性能。因此，粘合材料未来的创新应该寻求新的性能，而不是简单地修改现有技术。认为“生物活性”的粘连材料有助于改善恢复性治疗的预后。本文综述了近年来通过加入生物活性成分来实现牙科粘合剂的治疗性聚合物的方法。粘附性修复体的维护策略是本文研究的重点。关于治疗性牙科粘合剂的主要试验着眼于增加抗菌活性或再矿化效果。基于季铵盐化合物的抗菌树脂单体的应用受到了广泛的关注，纳米生物活性粒子或多离子释放玻璃填充物的负载不会影响载体聚合物的力学性能，因此被认为是有利的。这里描述的治疗性聚合物方法有可能提供临床益处。然而，这一类别的技术应用并不多，并未成功商业化。临床证据以及这些技术的进一步进步可以推动这些新型材料在临床上的应用。
Many recent adhesives on the market exhibit reasonable clinical performance. Future innovations in adhesive materials should therefore seek out novel properties rather than simply modifying existing technologies. It is proposed that adhesive materials that are “bio-active” could contribute to better prognosis of restorative treatments. This review examines the recent approaches used to achieve therapeutic polymers for dental adhesives by incorporating bio-active components. A strategy to maintain adhesive restorations is the focus of this paper. Major trials on therapeutic dental adhesives have looked at adding antibacterial activities or remineralization effects. Applications of antibacterial resin monomers based on quaternary ammonium compounds have received much research attention, and the loading of nano-sized bioactive particles or multiple ion-releasing glass fillers have been perceived as advantageous since they are not expected to influence the mechanical properties of the carrier polymer. The therapeutic polymer approaches described here have the potential to provide clinical benefits. However, not many technological applications in this category have been successfully commercialized. Clinical evidence as well as further advancement of these technologies can be a driving force to make these new types of materials clinically available.
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影响因子：
5
作者：
Imazato, S;Kuramoto, A;Peters, MC
通讯作者：
Peters, MC
影响因子：
5
作者：
He, Jingwei;Soderling, Eva;Vallittu, Pekka K.
通讯作者：
Vallittu, Pekka K.
影响因子：
4.5
作者：
Damm, Cornelia;Muensted, Helmut;Roesch, Alfons
通讯作者：
Roesch, Alfons
影响因子：
5.6
作者：
He J;Söderling E;Vallittu PK;Lassila LV
通讯作者：
Lassila LV
掺入新型可聚合季铵盐MAE-DB的树脂对变形链球菌的抗菌作用
DOI：
10.1002/jbm.b.32703
发表时间：
2012-07-01
影响因子：
3.4
作者：
Huang, Li;Sun, Xiang;Chen, Ji-Hua
通讯作者：
Chen, Ji-Hua