Prevalence of depression among people living with HIV in rural hospitals in South-Western Nigeria-Association with clinico-demographic factors.

Prevalence of depression among people living with HIV in rural hospitals in South-Western Nigeria-Association with clinico-demographic factors.
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DOI:
10.1186/s12981-023-00586-0
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发表时间:
2023-12-16
影响因子:
2.2
通讯作者:
--
中科院分区:
医学3区
文献类型:
--
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重度抑郁症是艾滋病毒感染者(PLWH)中最常见的神经精神疾病,并预示着他们的高发病率和死亡率。本研究估计了2020年9月至12月期间尼日利亚西南部两家提供抗逆转录病毒治疗(ART)服务的农村二级卫生机构中PLWH的患病率,并探讨了与抑郁症相关的因素。患者健康问卷-9 (PHQ-9)用于筛选和识别18岁及以上患有抑郁症的PLWH。使用SPSS version 23进行描述性统计、双变量和多变量分析。共有172名受访者接受了筛选。抑郁症患病率为16.3% (95% CI 11.1%, 22.7%)。轻度、中度和中度抑郁症分别在17名(9.9%)、8名(4.7%)和3名(1.7%)参与者中被确定。1名(0.6%)受访者有自杀意念。在患有抑郁症的PLWH中,20/28(71.4%)的年龄在40-59岁之间。所有参与者都没有服用抗抑郁药。与抑郁最相关的因素是高血压,校正后的奇比为9.8(95% CI 3.5-27.3, p < 0.0001)。该研究强调了在非洲提供抗逆转录病毒治疗服务的农村医院的艾滋病病毒感染者卫生保健人员中筛查抑郁症严重程度的重要性。合并高血压的PLWH患者更有可能患有某种形式的抑郁症。
Major depression is the most common neuropsychiatric disorder among people living with HIV (PLWH) and is predictive of high morbidity and mortality among them. This study estimated the prevalence and explored factors associated with depression among PLWH in two rural secondary health facilities providing anti-retroviral therapy (ART) services in Southwestern Nigeria between September and December 2020. The Patient Health Questionnaire-9 (PHQ-9) was used to screen and identify PLWH aged 18 years or older with depression. Descriptive statistics, bivariate and multivariate analyses were performed with SPSS version 23. A total of 172 respondents were screened. The prevalence of depression was 16.3% (95% CI 11.1%, 22.7%). Mild, moderate, and moderately severe depression was identified in 17 (9.9%), 8(4.7%) and 3(1.7%) of the participants, respectively. One (0.6%) respondent had suicidal ideation. Of PLWH with any depression, 20/28(71.4%) were within the 40–59 years of age range. None of the participants was on antidepressants. The factor most associated with depression was hypertension, with adjusted odd ratios of 9.8(95% CI 3.5–27.3, p < 0.0001). The study highlights the importance of screening for the severity of depression among PLWH in rural hospitals providing ART services in Africa. PLWH with comorbid hypertension were more likely to suffer from some form of depression.
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