The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysis.

The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysis.
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DOI:
10.1016/j.eclinm.2023.102255
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发表时间:
2023-11
期刊:
影响因子:
15.1
通讯作者:
Musekiwa, Alfred
Musekiwa, Alfred
中科院分区:
医学1区
文献类型:
--
作者:
Moyo-Chilufya, Maureen;Maluleke, Kuhlula;Kgarosi, Kabelo;Muyoyeta, Monde;Hongoro, Charles;Musekiwa, Alfred

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非传染性疾病(NCD)在艾滋病毒携带者(PLHIV)中正在增加,特别是在撒哈拉以南非洲(SSA)。我们确定了SSA地区PLHIV中非传染性疾病和非传染性疾病危险因素的患病率,以便为卫生政策制定者提供信息。我们对SSA地区PLHIV的非传染性疾病及其危险因素的流行情况进行了系统的回顾和荟萃分析。我们全面检索PubMed/MEDLINE、Scope us和EBSCOhost(CINAHL)电子数据库,查找2010年至2023年7月发表的来源。我们应用随机效应荟萃分析模型,使用STATA统计软件对结果进行汇总。系统评审方案在Propero上注册(注册号:CRD42021258769)。我们在这项荟萃分析中纳入了来自21个国家的188项研究。我们的研究结果表明,合并患病率估计为高血压(20.1%[95%CI:17.5-22.7])、抑郁症(30.4%[25.3-35.4])、糖尿病(5.4%[4.4-6.4])、宫颈癌(1.5%[0.1-2.9])、慢性呼吸道疾病(7.1%[4.0-10.3])、超重/肥胖(32.2%[29.7-34.7])、高胆固醇血症(21.3%[16.6-26.0])、代谢综合征(23.9%[19.5-28.7])、饮酒(21.3%[17.9-24.6])和吸烟(6.4%[5.2-7.7])。艾滋病毒携带者有很高的非传染性疾病及其危险因素,包括高血压、抑郁症、超重/肥胖、高胆固醇血症、代谢综合征和饮酒。我们建议加强卫生系统,使非传染性疾病和艾滋病毒服务能够更好地整合到南沙的公共卫生设施中。非传染性疾病的危险因素,如肥胖、高胆固醇血症和饮酒,可以通过健康促进活动来解决。有必要进一步研究大多数SSA地区艾滋病毒感染者中非传染性疾病的负担。这项研究没有得到任何资助。
Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in SSA to inform health policy makers. We conducted a systematic review and meta-analysis on the prevalence of NCDs and risk factors among PLHIV in SSA. We comprehensively searched PubMed/MEDLINE, Scopus, and EBSCOhost (CINAHL) electronic databases for sources published from 2010 to July 2023. We applied the random effects meta-analysis model to pool the results using STATA. The systematic review protocol was registered on PROSPERO (registration number: CRD42021258769). We included 188 studies from 21 countries in this meta-analysis. Our findings indicate pooled prevalence estimates for hypertension (20.1% [95% CI:17.5–22.7]), depression (30.4% [25.3–35.4]), diabetes (5.4% [4.4–6.4]), cervical cancer (1.5% [0.1–2.9]), chronic respiratory diseases (7.1% [4.0–10.3]), overweight/obesity (32.2% [29.7–34.7]), hypercholesterolemia (21.3% [16.6–26.0]), metabolic syndrome (23.9% [19.5–28.7]), alcohol consumption (21.3% [17.9–24.6]), and smoking (6.4% [5.2–7.7]). People living with HIV have a high prevalence of NCDs and their risk factors including hypertension, depression, overweight/obesity, hypercholesterolemia, metabolic syndrome and alcohol consumption. We recommend strengthening of health systems to allow for improved integration of NCDs and HIV services in public health facilities in SSA. NCD risk factors such as obesity, hypercholesterolemia, and alcohol consumption can be addressed through health promotion campaigns. There is a need for further research on the burden of NCDs among PLHIV in most of SSA. This study did not receive any funding.
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发表时间: 2018
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影响因子: 3.7
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影响因子: 5
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