Diet and inflammatory bowel disease: review of patient-targeted recommendations.
Diet and inflammatory bowel disease: review of patient-targeted recommendations.
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DOI：
10.1016/j.cgh.2013.09.063
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发表时间：
2014-10
影响因子：
12.6
通讯作者：
Lewisk, James
中科院分区：
文献类型：
--
作者：
Hou, Jason K.;Lee, Dale;Lewisk, James
关键词：
患者坚信饮食在炎症性肠病（IBD）的病因中以及在加重或减轻IBD的持续症状中的作用。在过去的几十年中，IBD的发病率和患病率的迅速增加强烈表明IBD的环境触发因素，其中之一可能是饮食模式。饮食可能影响肠道炎症的几种途径，如直接饮食抗原，改变肠道微生物组和影响胃肠道通透性。然而，改变饮食可以改变IBD自然史的数据很少，并且缺乏IBD患者的循证饮食指南。因此，患者寻求非医疗资源的饮食指导，如患者支持小组和未经证实的来源在互联网上。本综述的目的是确定针对IBD患者的饮食建议，并严格评估这些建议的营养价值。我们从结构化的互联网搜索和流行的定义饮食中回顾了IBD的患者针对性饮食信息。针对患者的饮食建议侧重于食物限制，并且高度冲突。需要高质量的饮食干预研究，以促进IBD患者循证饮食指南的制定。
Patients have strong beliefs about the role of diet in the cause of inflammatory bowel disease (IBD) and in exacerbating or alleviating ongoing symptoms from IBD. The rapid increase in the incidence and prevalence of IBD in the past several decades strongly suggests an environmental trigger for IBD, one of which may be dietary patterns. There are several pathways where diet may influence intestinal inflammation such as direct dietary antigens, altering the gut microbiome, and affecting gastrointestinal permeability. However, data that altering diet can change the natural history of IBD are scarce and evidence based dietary guidelines for patients with IBD are lacking. Patients therefore seek non-medical resources for dietary guidance such as patient support groups and unverified sources on the internet. The aim of this review is to identify patient-targeted dietary recommendations for IBD and to critically appraise the nutritional value of these recommendations. We review patient-targeted dietary information for IBD from structured internet searches and popular defined diets. Patient-targeted dietary recommendations focus on food restrictions and are highly conflicting. High quality dietary intervention studies are needed to facilitate creation of evidence-based dietary guidelines for patients with IBD.
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影响因子：
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