Integrity of white matter in the corpus callosum correlates with bimanual co-ordination skills.

Integrity of white matter in the corpus callosum correlates with bimanual co-ordination skills.
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DOI:
10.1016/j.neuroimage.2007.03.041
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发表时间:
2007
期刊:
影响因子:
5.7
通讯作者:
Paus T
Paus T
中科院分区:
医学1区
文献类型:
--
作者:
Johansen-Berg H;Della-Maggiore V;Behrens TE;Smith SM;Paus T

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大脑结构的变化可能反映了特定大脑系统功能特性的变化。因此,结构变化可能反映了行为表现的变化。在这里,我们使用弥散加权磁共振成像,以显示白质完整性的变化,在身体的一个特定区域的胼胝体是相关的表现,在一个双指甲协调任务的变化。当显示这种联系的胼胝体区域被用作概率束成像的种子时,产生了通往辅助运动区和尾侧扣带运动区的半球间通路。这为内侧壁运动区在双手协调中的作用提供了进一步的证据,并支持了这样一种观点,即大脑结构的变化反映了技能表现的个体差异。
Variation in brain structure may reflect variation in functional properties of specific brain systems. Structural variation may therefore reflect variation in behavioural performance. Here, we use diffusion-weighted magnetic resonance imaging to show that variation in white matter integrity in a specific region in the body of the corpus callosum is associated with variation in performance of a bimanual co-ordination task. When the callosal region showing this association is used as a seed for probabilistic tractography, inter-hemispheric pathways are generated to the supplementary motor area and caudal cingulate motor area. This provides further evidence for the role of medial wall motor areas in bimanual co-ordination and supports the idea that variation in brain structure reflects inter-individual differences in skilled performance.
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