Rapid transfer of abstract rules to novel contexts in human lateral prefrontal cortex.

Rapid transfer of abstract rules to novel contexts in human lateral prefrontal cortex.
复制标题

DOI:
10.3389/fnhum.2011.00142
复制
发表时间:
2011
影响因子:
2.9
通讯作者:
Braver TS
Braver TS
中科院分区:
医学3区
文献类型:
--
作者:
Cole MW;Etzel JA;Zacks JM;Schneider W;Braver TS

文献摘要

参考文献

被引文献

相似文献

灵活的适应性行为被认为依赖于外侧前额叶皮层(LPFC)内的抽象规则表征,但目前尚不清楚这些表征如何提供这种灵活性。我们最近证明人类可以在几秒钟内学习复杂的新任务。在这里,我们假设这种令人印象深刻的心理灵活性可能是由于 LPFC 中练习的规则表示快速转移到新的任务环境中而可能实现的。我们使用功能 MRI 和多变量模式分析测试了这一假设,对 64 项任务中的 LPFC 活动模式进行了分类。经过训练的分类器可以根据实践的任务活动模式识别抽象规则,并成功推广到新任务。这表明人类可以在 LPFC 中转移实践的规则表示来快速学习新任务,从而促进新环境中的认知表现。
Flexible, adaptive behavior is thought to rely on abstract rule representations within lateral prefrontal cortex (LPFC), yet it remains unclear how these representations provide such flexibility. We recently demonstrated that humans can learn complex novel tasks in seconds. Here we hypothesized that this impressive mental flexibility may be possible due to rapid transfer of practiced rule representations within LPFC to novel task contexts. We tested this hypothesis using functional MRI and multivariate pattern analysis, classifying LPFC activity patterns across 64 tasks. Classifiers trained to identify abstract rules based on practiced task activity patterns successfully generalized to novel tasks. This suggests humans can transfer practiced rule representations within LPFC to rapidly learn new tasks, facilitating cognitive performance in novel circumstances.
DOI: 10.1523/jneurosci.5389-05.2006
发表时间: 2006-05-03
影响因子: 5.3
作者:
Goldberg, RF;Perfetti, CA;Schneider, W
通讯作者: Schneider, W
DOI: 10.1152/jn.00910.2002
发表时间: 2003-11-01
影响因子: 2.5
作者:
Bunge, SA;Kahn, I;Wagner, AD
通讯作者: Wagner, AD
DOI: 10.1002/mrm.10171
发表时间: 2002-06-01
影响因子: 3.3
作者:
Griswold, MA;Jakob, PM;Haase, A
通讯作者: Haase, A
DOI: 10.1016/j.neuroimage.2007.03.071
发表时间: 2007-08-01
期刊: NEUROIMAGE
影响因子: 5.7
作者:
Cole, Michael W.;Schneider, Walter
通讯作者: Schneider, Walter
DOI: 10.1037/a0024695
发表时间: 2011-11-01
影响因子: 4.1
作者:
Burgess, Gregory C.;Gray, Jeremy R.;Braver, Todd S.
通讯作者: Braver, Todd S.