Spore formation in Bacillus subtilis.

Spore formation in Bacillus subtilis.
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DOI:
10.1111/1758-2229.12130
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发表时间:
2014-06
影响因子:
3.3
通讯作者:
Ramamurthi KS
Ramamurthi KS
中科院分区:
生物学3区
文献类型:
--
作者:
Tan IS;Ramamurthi KS

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虽然原核生物通常经历二次分裂以产生两个相同的子细胞,但一些原核生物能够经历不同的发育途径,产生具有不同细胞形态和命运的子细胞。其中一个例子是枯草芽孢杆菌中的一种叫做产孢子的发育程序,它发生在环境压力的条件下。长期以来,产孢子系统一直被用来帮助阐明发育生物学的基本过程,包括转录调控、细胞间信号转导、膜重塑、蛋白质定位和细胞命运决定。本文综述了近年来为进一步了解原核细胞在孢子形成过程中的分化及其潜在应用所做的一些工作。
Although prokaryotes ordinarily undergo binary fission to produce two identical daughter cells, some are able to undergo alternative developmental pathways that produce daughter cells of distinct cell morphology and fate. One such example is a developmental program called sporulation in the bacterium Bacillus subtilis, which occurs under conditions of environmental stress. Sporulation has long been used as a model system to help elucidate basic processes of developmental biology including transcription regulation, intercellular signaling, membrane remodeling, protein localization, and cell fate determination. This review highlights some of the recent work that has been done to further understand prokaryotic cell differentiation during sporulation and its potential applications.
DOI: 10.1016/0092-8674(91)90238-t
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期刊: CELL
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