Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories.
Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories.
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DOI：
10.1126/sciadv.adg6034
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发表时间：
2023-08-02
期刊：
影响因子：
13.6
通讯作者：
Telford, Maximilian J.
中科院分区：
文献类型：
--
作者：
Piovani, Laura;Leite, Daniel J.;Guerra, Luis Alfonso Yanez;Simpson, Fraser;Musser, Jacob M.;Salvador-Martinez, Irepan;Marletaz, Ferdinand;Jekely, Gaspar;Telford, Maximilian J.
浮游幼虫阶段在动物中广泛存在，但目前还不清楚幼虫是否存在于动物的最后一个共同祖先中，或者它们是否由于共同的选择压力而多次进化。许多海洋幼虫至少在表面上是相似的;它们很小，通过纤毛带的跳动游泳，并用顶端器官感知环境。为了了解这些相似之处，我们已经产生了单细胞图谱海洋幼虫从两个动物门，并比较了它们的细胞类型。我们发现睫状带细胞和神经元的顶端器官在两个幼虫指向可能的同源性，这些结构之间有明显的相似性，这表明一个单一的起源内Spiralia幼虫。我们还发现了几个分支特定的创新，在每个幼虫，包括不同的肌细胞和壳腺细胞的牡蛎幼虫。牡蛎壳腺细胞表达许多最近进化的基因，使以前的基因年龄估计担轮幼虫的起源太年轻。扁形动物和软体动物幼虫的单细胞图谱揭示了同源细胞类型和门特异性创新。
Pelagic larval stages are widespread across animals, yet it is unclear whether larvae were present in the last common ancestor of animals or whether they evolved multiple times due to common selective pressures. Many marine larvae are at least superficially similar; they are small, swim through the beating of bands of cilia, and sense the environment with an apical organ. To understand these similarities, we have generated single-cell atlases for marine larvae from two animal phyla and have compared their cell types. We found clear similarities among ciliary band cells and between neurons of the apical organ in the two larvae pointing to possible homology of these structures, suggesting a single origin of larvae within Spiralia. We also find several clade-specific innovations in each larva, including distinct myocytes and shell gland cells in the oyster larva. Oyster shell gland cells express many recently evolved genes that have made previous gene age estimates for the origin of trochophore larvae too young. Single-cell atlases of platyhelminth and mollusc larvae reveal homologous cell types and phylum-specific innovations.
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影响因子：
4.6
作者：
De Oliveira, A. L.;Calcina, A.;Wanninger, A.
通讯作者：
Wanninger, A.
DOI：
10.1007/s00018-017-2697-4
发表时间：
2018-04
期刊：
Cellular and molecular life sciences : CMLS
影响因子：
--
作者：
Thiruvalluvan M;Barghouth PG;Tsur A;Broday L;Oviedo NJ
通讯作者：
Oviedo NJ
影响因子：
12.3
作者：
García-Castro H;Kenny NJ;Iglesias M;Álvarez-Campos P;Mason V;Elek A;Schönauer A;Sleight VA;Neiro J;Aboobaker A;Permanyer J;Irimia M;Sebé-Pedrós A;Solana J
通讯作者：
Solana J
影响因子：
10.7
作者：
Achim K;Eling N;Vergara HM;Bertucci PY;Musser J;Vopalensky P;Brunet T;Collier P;Benes V;Marioni JC;Arendt D
通讯作者：
Arendt D
影响因子：
4.4
作者：
Conzelmann M;Williams EA;Krug K;Franz-Wachtel M;Macek B;Jékely G
通讯作者：
Jékely G